The metabolic diseases and disorders are a cluster of chronic conditions such as obesity, glucose tolerance impairment, insulin resistance, cancer and many more, ultimately leading to endocrine dysfunction. Due to changing lifestyle at a swift pace in this 21st century, the humans have become more prone to metabolic changes or metabolic mutations causing progression of the metabolic disorders. Several conventional therapeutic approaches are used in the management of these debilitating disorders, but they can only manage the condition lifetime. For complete cure, the World Health Organization focused mainly on the traditional herbal drugs and gained knowledge about their utilization as therapeutic agents in the management of several diseases. The ancient medical treatments suggest that these metabolic disorders can be completely cured by the right use of herbal medicines. In the past few decades, the consumption of herbal dietary supplements has increased significantly and garnered greater attention to their therapeutic effects. A higher lot of patients have started consuming these herbals and dietary supplements in their diet for management of chronic metabolic diseases. Due to an increase demand, the herbal alternatives are now even available over the counter, and this has encouraged the researchers to explore more healthier and herbal alternatives to the traditional conventional medicines as they pose better efficacy with minimum side effects. The disease progression is mainly divided into two stages, and the formulations are produced accordingly. These herbal medicines represent an attractive adjuvant to the conventional therapy as they are easily accessible and have fewer toxic effects. Hence the herbal products are being explored by various researchers all around the world and their efficiency are under studies to evaluate their role in management and cure of endocrine and metabolic disorders.
This special issue will focus on the following directions:
- chemical compounds extracted form plants with beneficial effects in endocrine diseases (e.g. diabetes mellitus, metabolic syndrome, polycystic ovary syndrome, hypothyroidism, etc.);
- functional foods that improve the parameters of endocrine disorders (hormone values, mineral balance);
- personalized diets with proven benefits or diets of current interest in managing endocrine pathology because of their pleiotropic effects such as antioxidant, anti-inflammatory, hypoglycemic or hypotensive effects;
- in vitro and in vivo studies on rodents or humans exploring the impact of natural products in improving specific endocrine conditions and the general wellbeing of these patients;
natural products and modern modalities for delivery of chemical compounds (liposomes, nanoparticles, etc.) for better cellular delivery and improved effect.
Prof. Habil. PhD. Simona Bungau and Assoc. Prof. Dr. Tapan Behl
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