Human eye likes a forward camera of brain, over 70 % information we got is through eye. Normal vision acuity is the requirement of daily life for every individual person. The eye disease shares many common characteristics with systemic diseases. Eye diseases, including cataracts, diabetic retinopathy, glaucoma, Grave’s diseases, Sjügren syndrome and inflammatory disease often see in medical practices, may be secondary to systemic diseases, Importantly, certainly complications in eye can serve a diagnostic implication for systemic disease for example diabetes and hypotension and etc.
It is estimated that 38 million people are blind and 110 million are vision-impaired Worldwide, importantly, majority of vision loss is preventable and treatable. The treatment and prevention of eye diseases is based on the understanding of the pathogenesis of the diseases, which can lead to interfere the pathogenesis of the disease process or cure the diseases, therefore, basic and clinical research may play an essential role in preserving and rescuing vision acuity.
The common vision impairing eye diseases are complex eye diseases including but not limited to corneal diseases, glaucoma, cataract, uveitis, age related macular degeneration, diabetic retinopathy, intraocular tumors and advanced myopia, ocular trauma and etc. The pathogenesis of eye diseases may be linked to genetic (gene mutation, SNPs) /epigenetics abnormal, inflammatory and immune response, degeneration, angiogenesis, oxidative stress damage and deucedly wound healing, which may contribute to vision impairing. Even a remarkable progress of eye and vison research has been made in last decades, the pathogenesis of those complex eye diseases is still under-investigation, hence, in the upcoming special issue (SI), the updated studies in the vision impairing eye diseases and vision function will be addressed. original articles and review paper are welcome. We hope the special issue will provide the most advanced knowledge in understanding of the pathogenesis of eye diseases, vision function and its potential therapeutic intervention. The launch of the SI may help to establish a pavement for future SI such as inflammatory eye disease, degenerative eye disease, angiogenic eye diseases, ocular tumor, fibrotic eye diseases, genetic eye diseases and eye diseases with epigenetic alteration, respectively.
Prof. Shikun He
Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2500 USD. Submitted manuscripts should be well formatted in good English.
Endoplasmic reticulum stress as a novel target to inhibit transdifferentiation of human retinal pigment epithelial cells
Sha Ouyang and Shikun He
Mechanism of Semaphorin 3A Mediated Retinal Müller Cell Activation in High Glucose Environment in Terms of Inflammation and Oxidative Stress
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- The Significance of the Ocular Adverse Effect Induced by Systemic Taxane ApplicationYa-Ting Ye, Zi-Yi Zhou, Li-Shi Wen, Yu Sun, ... Guo-Rui DouFront. Biosci. (Landmark Ed) 2022, 27(6), 171; https://doi.org/10.31083/j.fbl270617189Downloads1Citations266Views
- Harnessing the Neuroprotective Behaviors of Müller Glia for Retinal RepairJuan S. Peña, Maribel VazquezFront. Biosci. (Landmark Ed) 2022, 27(6), 169; https://doi.org/10.31083/j.fbl2706169148Downloads2Citations319Views
- In Vitro Corneal and Conjunctival Wound-Healing Assays as a Tool for Antiglaucoma Prostaglandin Formulation CharacterizationHong Liang, Christophe Baudouin, Philippe Daull, Jean-Sébastien Garrigue, Françoise Brignole-BaudouinFront. Biosci. (Landmark Ed) 2022, 27(5), 147; https://doi.org/10.31083/j.fbl2705147107Downloads2Citations323Views
- Age Distribution of 4526 Surgically Excised Specimens of Eye Tumors by Histopathological Examination in ChinaXiaohua Li, Guishuang Ying, Xiaohui Liu, Min Yuan, Ruijie YinFront. Biosci. (Landmark Ed) 2022, 27(4), 132; https://doi.org/10.31083/j.fbl270413254Downloads2Citations274Views
- Neovascular Remodeling and Subretinal Fibrosis as Biomarkers for Predicting Incomplete Response to Anti-VEGF Therapy in Neovascular Age-Related Macular DegenerationJing Wu, Jingfa ZhangFront. Biosci. (Landmark Ed) 2022, 27(4), 135; https://doi.org/10.31083/j.fbl2704135172Downloads1Citations455Views
- Safety and Efficacy of Systemic Anti-Scg3 Therapy to Treat Oxygen-Induced RetinopathyChang Dai, Hong Tian, Amit Bhatt, Guanfang Su, ... Wei LiFront. Biosci. (Landmark Ed) 2022, 27(4), 130; https://doi.org/10.31083/j.fbl270413074Downloads2Citations296Views
- Long-Term Ultrastructural Outcomes of Autologous Transplantation of Retinal Pigment Epithelium—Partial Thickness Choroid (RPE-PTC) Sheet in RabbitsXue Ding, Taoran Zhang, Ying Hong, Xin Chang, ... Yuntao HuFront. Biosci. (Landmark Ed) 2022, 27(3), 106; https://doi.org/10.31083/j.fbl270310668Downloads317Views
- Mesenchymal stem cell derived exosomes-based immunological signature in a rat model of corneal allograft rejection therapyZhe Jia, Ying Lv, Wanjun Zhang, Xiaomin Zhang, ... Shaozhen ZhaoFront. Biosci. (Landmark Ed) 2022, 27(3), 86; https://doi.org/10.31083/j.fbl2703086180Downloads4Citations430Views
- A new injury severity scale for ocular complications following cosmetic filler injectionShancheng Si, Linying Lai, Xue Ding, Wei Su, ... Yuntao HuFront. Biosci. (Landmark Ed) 2022, 27(2), 59; https://doi.org/10.31083/j.fbl2702059143Downloads4Citations345Views
- Comparison of clinical performance and subjective outcomes between two diffractive trifocal intraocular lenses (IOLs) and one monofocal IOL in bilateral cataract surgeryAurelio Imburgia, Francesco Gaudenzi, Kira Mularoni, Gloria Mussoni, Alessandro MularoniFront. Biosci. (Landmark Ed) 2022, 27(2), 41; https://doi.org/10.31083/j.fbl2702041195Downloads1Citations426Views
- Ischemic index and distribution of retinal capillary non-perfusion in neovascular glaucomaCharles DeBoer, Brandon Wong, Hossein AmeriFront. Biosci. (Landmark Ed) 2022, 27(1), 24; https://doi.org/10.31083/j.fbl270102472Downloads1Citations248Views
- An animal study on the effect of topically administered ambroxol for dry eyeZixuan Wang, Li Yu, Shaochong Zhang, Zhenhan Wang, Mingwu WangFront. Biosci. (Landmark Ed) 2022, 27(1), 4; https://doi.org/10.31083/j.fbl2701004139Downloads399Views