Natural products in the treatment of cancers: Molecular mechanisms and clinical prospects

Dear Colleagues,

Cancer is regarded as the 2nd leading causes of death worldwide, irrespective of age, sex and locality. Indeed, it causing a huge economic burden and affecting both individuals and health care systems. The therapeutic approaches including surgery, chemotherapy and radiotherapy, depending upon the individual condition and therefore that varies from case to case. From clinical perspectives, there are several agents in practice, however, facing many challenges in term of sensitivity, efficacy, and or safety. In the light of therapeutic potential of natural products as anticancer agents such as vincristine, vinblastine, Taxol etc., it is strongly believed this commodity has outstanding impending but need scientific studies. There are several new isolated compounds have been reported to be in preclinical and clinical stages. In this connection, the development of new techniques has greatly facilitated the cancer research/drug discovery from natural agents.

In this special issue, we will focus on various natural products and their isolates with strong effects as anticancer in both preclinical and clinical phases. The evidence-based studies on natural isolates such as flavonoids, alkaloids, glycosides, terpenes etc. or individual single compound with detail mechanistic studies that could be candidates of the clinical studies. The types may be review, meta-analysis and research articles in this regard will be welcome. Similarly, the clinical trials on natural anticancer therapies are strongly accepted.

Prof. Dr. Haroon Khan and Prof. Dr. Esra Küpeli Akkol

Guest Editor

Manuscripts should be submitted via our online editorial system at https://imr.propub.com by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website. Research articles, reviews as well as short communications are preferred. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office to announce on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2500 USD. Submitted manuscripts should be well formatted in good English.