IMR Press / FBL / Special Issues / 1326790361603276802
Genetically-modified animals as research models in development and disease
Submission deadline: 31 December 2012
Special Issue Editor
Vicente Andres
Ph.D., Dept. of Molecular and Cellular Pathology and Therapy, Jaime Roig 11, 46010 Valencia (Spain)
Interests: 60 publications, 16 grants, Editor of Frontiers in Bioscience, Cardiologia Practica
Keywords
Genes and Genetics
Molecular Biology
Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. The Article Processing Charge (APC) in this open access journal is 2500 USD. Submitted manuscripts should be well formatted in good English.

Published Paper (37 Papers)
Open Access Article
Regulation of cell proliferation and differentiation in the kidney
Neal I. Alcalay, Gregory B. Vanden Heuvel
Front. Biosci. (Landmark Ed) 2009, 14(13), 4978–4991; https://doi.org/10.2741/3582
4
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11
Citations
7
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Open Access Article
Mouse models to study angiogenesis in the context of cardiovascular diseases
Thierry Couffinhal, Pascale Dufourcq, Laurent Barandon, Lionel Leroux, Cecile Duplaa
Front. Biosci. (Landmark Ed) 2009, 14(9), 3310–3325; https://doi.org/10.2741/3454
2
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12
Citations
3
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Open Access Article
The use of genetically engineered model systems for research on human aging
Guenter Lepperdinger, Peter Berger, Michael Breitenbach, Kai-Uwe Frohlich, ... Pidder Jansen-Durr
Front. Biosci. (Landmark Ed) 2008, 13(18), 7022–7031; https://doi.org/10.2741/3207
6
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6
Citations
3
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Open Access Article
Control of atherosclerotic plaque vulnerability: insights from transgenic mice
Sylvia Heeneman, Esther Lutgens, Kitty B Schapira, Mat J A P Daemen, Erik A L Biessen
Front. Biosci. (Landmark Ed) 2008, 13(16), 6289–6313; https://doi.org/10.2741/3155
3
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14
Citations
5
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Open Access Article
Knock-out mouse models of proprotein convertases: unique functions or redundancy?
John W.M. Creemers, Abdel-Majid Khatib
Front. Biosci. (Landmark Ed) 2008, 13(13), 4960–4971; https://doi.org/10.2741/3055
40
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69
Citations
10
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Open Access Article
HIV-1 transgenic expression in mice induces selective atrophy of fast-glycolytic skeletal muscle fibers
Antonio L. Serrano, Merce Jardi, Monica Suelves, Paul E. Klotman, Pura Munoz-Canoves
Front. Biosci. (Landmark Ed) 2008, 13(8), 2797–2805; https://doi.org/10.2741/2886
5
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10
Citations
6
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Open Access Article
Of mice without pockets: mouse models to study the function of Rb family proteins
Anxo Vidal, Carmen Carneiro, Juan B. Zalvide
Front. Biosci. (Landmark Ed) 2007, 12(7), 4483–4496; https://doi.org/10.2741/2403
2
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11
Citations
3
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Open Access Article
An insight into the pathophysiology of thrombosis in antiphospholipid syndrome
Ivan G Palomo, Fabian M Segovia, Marcelo L Alarcon, Barbara Y Fuentes, ... Ricardo Forastiero
Front. Biosci. (Landmark Ed) 2007, 12(8), 3093–3103; https://doi.org/10.2741/2297
5
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12
Citations
8
Views
Open Access Article
Retromer and sorting nexins in development
Marcel Verges
Front. Biosci. (Landmark Ed) 2007, 12(10), 3825–3851; https://doi.org/10.2741/2355
4
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26
Citations
8
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2
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9
Citations
1
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3
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21
Citations
1
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Open Access Article
Murine models to investigate the influence of diabetic metabolism on the development of atherosclerosis and restenosis
Herminia Gonzalez-Navarro, Deborah J. Burks, Vicente Andres
Front. Biosci. (Landmark Ed) 2007, 12(7), 4439–4455; https://doi.org/10.2741/2400
6
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15
Citations
4
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17
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39
Citations
15
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Open Access Article
Function and regulation of the complement system in cardiovascular diseases
Riina Oksjoki, Petri T Kovanen, Seppo Meri, Markku O Pentikainen
Front. Biosci. (Landmark Ed) 2007, 12(12), 4696–4708; https://doi.org/10.2741/2419
20
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59
Citations
7
Views
Open Access Article
Role of Bcl-2 family members on apoptosis: what we have learned from knock-out mice
Ramon Roset, Laura Ortet, Gabriel Gil-Gomez
Front. Biosci. (Landmark Ed) 2007, 12(12), 4722–4730; https://doi.org/10.2741/2421
12
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46
Citations
2
Views
Open Access Article
Age-related cardiac deterioration: insights from Drosophila
Robert J Wessells, Rolf Bodmer
Front. Biosci. (Landmark Ed) 2007, 12(1), 39–48; https://doi.org/10.2741/2047
5
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18
Citations
9
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Open Access Article

Type-2 diabetic Leprdb/db mice show a defective microvascular phenotype under basal conditions and an impaired response to angiogenesis gene therapy in the setting of limb ischemia

Costanza Emanueli, Andrea Caporali, Nicolle Krankel, Brunella Cristofaro, ... Paolo Madeddu
Front. Biosci. (Landmark Ed) 2007, 12(6), 2003–2012; https://doi.org/10.2741/2205
18
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31
Citations
16
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Open Access Article
The GCK II and III subfamilies of the STE20 group kinases
Celia María Pombo, Thomas Force, John Kyriakis, Emilio Nogueira, ... Juan Zalvide
Front. Biosci. (Landmark Ed) 2007, 12(3), 850–859; https://doi.org/10.2741/2107
16
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38
Citations
17
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Open Access Article
The risk for cardiovascular disease in women: from estrogens to selective estrogen receptor modulators
Antonio Cano, Carlos Hermenegildo, Pilar Oviedo, Juan Jose Tarín
Front. Biosci. (Landmark Ed) 2007, 12(1), 49–68; https://doi.org/10.2741/2048
1
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4
Citations
3
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Open Access Article
Animal models for the study of liver regeneration: role of nitric oxide and prostaglandins
Sonsoles Hortelano, Miriam Zeini, Marta Casado, Paloma Martín-Sanz, Lisardo Boscá
Front. Biosci. (Landmark Ed) 2007, 12(1), 13–21; https://doi.org/10.2741/2045
8
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11
Citations
5
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Open Access Article
Genetically engineered mice as a model for studying cardiac arrhythmias
Juan Tamargo, Ricardo Caballero, Lucía Núñez, Ricardo Gómez, ... Eva Delpón
Front. Biosci. (Landmark Ed) 2007, 12(1), 22–38; https://doi.org/10.2741/2046
9
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16
Citations
13
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Open Access Article
Cell fusion: biological perspectives and potential for regenerative medicine
Manuel Alvarez-Dolado
Front. Biosci. (Landmark Ed) 2007, 12(1), 1–12; https://doi.org/10.2741/2044
20
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31
Citations
15
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Open Access Article
Yeast as a model system to study glucose-mediated signalling and response
Pascual Sanz
Front. Biosci. (Landmark Ed) 2007, 12(6), 2358–2371; https://doi.org/10.2741/2238
19
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11
Citations
14
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Open Access Article
Plasma insulin levels predict the development of atherosclerosis when IRS2 deficiency is combined with severe hypercholesterolemia in apolipoprotein E-null mice
Herminia Gonzalez-Navarro, Marian Vila-Caballer, Maria F. Pastor, Angela Vinue, ... Vicente Andres
Front. Biosci. (Landmark Ed) 2007, 12(6), 2291–2298; https://doi.org/10.2741/2231
3
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19
Citations
5
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Open Access Article
Cyclooxygenase 2: understanding the pathophysiological role through genetically altered mouse models
Paloma Martín Sanz, Sonsoles Hortelano, Lisardo Bosca, Marta Casado
Front. Biosci. (Landmark Ed) 2006, 11(3), 2876–2888; https://doi.org/10.2741/2016
3
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15
Citations
7
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Open Access Article
Atheroma development in apolipoprotein E-null mice is not affected by partial inactivation of PTEN
Vicente Andrés, Marisol Gascón-Irún, Pier Paolo Pandolfi, Herminia González-Navarro
Front. Biosci. (Landmark Ed) 2006, 11(3), 2739–2745; https://doi.org/10.2741/2003
1
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4
Citations
3
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Open Access Article
Antiatherogenic role of high-density lipoproteins: insights from genetically engineered-mice
Joan Carles Escola-Gil, Laura Calpe-Berdiel, Xavier Palomer, Vicent Ribas, ... Francisco Blanco-Vaca
Front. Biosci. (Landmark Ed) 2006, 11(2), 1328–1348; https://doi.org/10.2741/1887
15
Citations
0
Views
Open Access Article
Cyclins and CDKS in development and cancer: lessons from genetically modified mice
David Santamaria, Sagrario Ortega
Front. Biosci. (Landmark Ed) 2006, 11(1), 1164–1188; https://doi.org/10.2741/1871
29
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118
Citations
12
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Open Access Article
Controlled gene activation and inactivation in the mouse
Moisés Mallo
Front. Biosci. (Landmark Ed) 2006, 11(1), 313–327; https://doi.org/10.2741/1799
23
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32
Citations
12
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Open Access Article
Endometriosis: harmful survival of an ectopic tissue
Janos Garai, Valeria Molnar, Tamas Varga, Miklos Koppan, ... Jozsef Bodis
Front. Biosci. (Landmark Ed) 2006, 11(1), 595–619; https://doi.org/10.2741/1821
12
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41
Citations
19
Views
Open Access Article
New animal models to study the role of tyrosinase in normal retinal development
Alfonso Lavado, Lluis Montoliu
Front. Biosci. (Landmark Ed) 2006, 11(1), 743–752; https://doi.org/10.2741/1832
20
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22
Citations
7
Views
Open Access Article
Understanding the role of dietary components on atherosclerosis using genetic engineered mouse models
Alfonso J. Sarria, Joaquin C. Surra, Sergio Acin, Ricardo Carnicer, ... Jesus Osada
Front. Biosci. (Landmark Ed) 2006, 11(1), 955–967; https://doi.org/10.2741/1852
3
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25
Citations
4
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Open Access Article
Mammalian genome targeting using site-specific recombinases
Angel Luis García-Otín, Florian Guillou
Front. Biosci. (Landmark Ed) 2006, 11(1), 1108–1136; https://doi.org/10.2741/1867
38
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78
Citations
51
Views
Open Access Article
Stem cells for cardiac repair: state of the art
Gianluigi Condorelli, Cesare Peschle
Front. Biosci. (Landmark Ed) 2005, 10(3), 3143–3150;
1
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Open Access Article
The plasminogen activation system in skeletal muscle regeneration: antagonistic roles of urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1)
Monica Suelves, Berta Vidal, Vanessa Ruiz, Bernat Baeza-Raja, ... Pura Munoz-Canoves
Front. Biosci. (Landmark Ed) 2005, 10(3), 2978–2985; https://doi.org/10.2741/1754
15
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25
Citations
3
Views
Open Access Article
Vitamin D and cancer: an update of in vitro and in vivo data
Paloma Ordonez-Moran, Maria Jesus Larriba, Natalia Pendas-Franco, Oscar Aguilera, ... Alberto Munoz
Front. Biosci. (Landmark Ed) 2005, 10(3), 2723–2749; https://doi.org/10.2741/1731
5
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79
Citations
38
Views
Open Access Article
Transcriptional profiling of early onset diet-induced atherosclerosis in apolipoprotein E-deficient mice
Claudia Castro, Josep María Campistol, Domingo Barettino, Vicente Andrés
Front. Biosci. (Landmark Ed) 2005, 10(2), 1932–1945; https://doi.org/10.2741/1669
1
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2
Citations
1
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