IMR Press / FBL / Special Issues / 1326789565906059265

Epigenetics in development and cancer

Submission deadline: 31 December 2021
Special Issue Editors
  • Xiao-Jian Sun
    Shanghai Institute of Hematology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine
    Interests: Epigenetic and Transcriptional Regulation Mechanisms in Development and Cancer
  • Lan Wang
    Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
    Interests: Hematopoietic Stem Cell; Hematopoietic Malignancy; Targeted Therapy
Special Issue Information

Dear Colleagues,

Epigenetic regulatory mechanisms play pivotal roles in both normal development and diseases such as cancer. Of special note is that the cancer actually “re-uses” many of the mechanisms in embryonic development to survive, grow, and invade into other tissues; therefore, it will be useful to compare them in the same special issue. Recent genome-wide studies have led to the discovery of many previously unrecognized cancer-causing genes. An important category of these genes are epigenetic regulators. Exploring the mechanism of action of these genes (and their mutated versions) in the processes of tumorigenesis is critically important to understand the biology of human cancer, and these mechanisms in turn will also further our understanding of normal development, as well as the development-related genetic diseases.

Prof. Xiao-Jian Sun and Prof. Lan Wang

Guest Editors


Keywords
Histone Modification
DNA Methylation
Mutation
Embryogenesis
Leukemia and Lymphoma
Manuscript Submission Information

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Published Paper (2 Papers)
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