IMR Press / FBL / Volume 8 / Issue 4 / DOI: 10.2741/1017

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Protein arrays, an excellent tool in biomedical research
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1 Division of Research, Department of Gynecology and Obstetrics, Emory University School of Medicine, 1639 Pierce Drive, Atlanta, GA 30322, USA
Front. Biosci. (Landmark Ed) 2003, 8(4), 559–576;
Published: 1 May 2003

Although excellent progress has been made in simultaneous analysis of the whole genome, great challenge remains in the highly paralleled analysis of proteome. The development of protein arrays represents a major technology advance in the proteomics field. Advances in protein array technology include chemical surfaces, capture reagents, detection methods and arraying devices. Protein arrays can be classified into different groups. Potential applications of protein arrays include: 1) measurement of protein expression; 2) identification of interactions between protein-protein, protein-DNA and protein-small molecule; 3) analysis of protein modifications; and 4) determination of antibodies. Such protein array technology holds great promise in biomedical research and clinical applications.

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