IMR Press / FBL / Volume 7 / Issue 4 / DOI: 10.2741/A814

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
The zebrafish as a model system for human disease
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1 Centre for Cellular & Molecular Biology, School of Biological & Chemical Sciences, Deakin University, Burwood, Victoria 3125, Australia
2 Cytokine Biology Laboratory, Ludwig Institute for Cancer Research, Melbourne Tumor Biology Branch, The Royal Melbourne Hospital, Victoria 3050, Australia
Academic Editor:Pudur Jagadeeswaran
Front. Biosci. (Landmark Ed) 2002, 7(4), 827–833; https://doi.org/10.2741/A814
Published: 1 April 2002
(This article belongs to the Special Issue The zebrafish as a model for human disease)
Abstract

The zebrafish (Danio rerio) has been widely utilised for the study of developmental biology, which has lead to the evolution of sophisticated cellular and molecular approaches. More recently, the rapid progress of various zebrafish genomic infrastructure initiatives is facilitating the development of zebrafish models of human disease. This review aims to describe several representative examples of how the zebrafish can be successfully used to identify novel genes and assign gene function, providing invaluable clues to human pathophysiology.

Keywords
Zebrafish
Disease
Review
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