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Article
Apoptosis - when the cells begin to dance
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Department of Medical Biology and Genetics, Charles University Faculty of Medicine in Hradec Kralove, Simkova 870, 500 01 Hradec Kralove I, Czech Republic
Front. Biosci. (Landmark Ed) 2000, 5(5), 1–2;
https://doi.org/10.2741/rudolf
Published: 1 September 2000
Abstract
We present a 24-hour time-lapse videosequence of in vitro behavior of Hep-2 cells treated with 10 µg/ml Etoposide, a topoisomerase II inhibitor. The cell behavior was recorded by a Mitsubishi video recorder, HS-S5600. In the presented sequence, we show the typical cell rounding accompanied by formation of numerous pseudopodia and rapid rhythmical contractions, so called membrane blebbing known as "dance of death".
Keywords
Apoptosis
Blebbing
Detection
In vitro
Time-lapse Videomicroscopy