IMR Press / FBL / Volume 4 / Issue 4 / DOI: 10.2741/sandell

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
Developmental patterns of cartilage
Show Less
1 Department of Orthopaedic Surgery, Barnes-Jewish Hospital at Washington University School of Medicine, 216 South Kingshighway, St. Louis, Missouri 63110, USA
Academic Editor:Charles Malemud
Front. Biosci. (Landmark Ed) 1999, 4(4), 731–742; https://doi.org/10.2741/sandell
Published: 15 October 1999
(This article belongs to the Special Issue Fundamental pathways in osteoarthritis)
Abstract

The current state of knowledge of cartilage differentiation leaves many questions unanswered. This review provides an up-to-date examination of current thinking on the subject of developmental patterns in cartilage formation. We will discuss the current model of limb elongation as well as the molecular aspects of chondrogenesis and growth plate formation. This will then be compared with the limited information currently known about the molecular aspects of osteoarthritis.

Keywords
Hedgehog
Cartilage
Development
BMP
FGF
Limb
Review
Share
Back to top