IMR Press / FBL / Volume 3 / Issue 5 / DOI: 10.2741/A373

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Article
Mycobacterial lipids: a historical perspective
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1 Universite Paul Sabatier (Toulouse 3) and Institut de Pharmacologie et de Biologie Structurale du CNRS, 205 route de Narbonne, 31077 Toulouse, Cedex, France
Front. Biosci. (Landmark Ed) 1998, 3(5), 164–174; https://doi.org/10.2741/A373
Published: 1 October 1998
Abstract

Mycobacterial lipids have been studied for more than 70 years, due to the fascinating diversity of their structures and biological activities. A historical perspective, and the present status on the structure and activity of major lipids of the outer envelope of mycobacterial cells are presented : mycolic acids, which are main constituents of the cell wall, and glycolipids known for toxic or immunological properties (cord factor, SL, DAT, PGL, GPL, LOS, LAM). As far as possible, it was tried to distinguish between experimentally established knowledge and currently accepted speculations.

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