IMR Press / FBL / Volume 26 / Issue 3 / DOI: 10.2741/4902

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review
Feed your microbiome and your heart: The gut-heart axis
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1 AESKU.KIPP Institute, Wendelsheim, Germany
Send correspondence to: Aaron Lerner, AESKU.KIPP Institute. Mikroforum Ring 2, 55234 Wendelsheim, Germany, Tel: 49-6734-9622-1010, Fax: 49-6734-9622-2222, E-mail: aaronlerner1948@gmail.com
Front. Biosci. (Landmark Ed) 2021, 26(3), 468–477; https://doi.org/10.2741/4902
Published: 1 October 2020
Abstract

Cardiovascular and metabolic diseases are the leading causes of disability, morbidity, and mortality worldwide. Genetics plays an important role, but environmental factors change the game and hold the potential for prevention, reversibility, and applied therapy. Nutrition, phenotype, and behavior of microorganisms, intestinal eco-events, and intestinal permeability play a crucial role in the induction of diseases. The present mini-review summarizes nutrients, diets, microbial manipulations, and tight junction function modifiers that might prevent, modulate, or treat certain diseases.

Keywords
Heart
Gut
Microbiome
Cardiovascular disease
Nutrition
Mechanisms
Pathways
Review
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