IMR Press / FBL / Volume 23 / Issue 3 / DOI: 10.2741/4602

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.


DNA replication machinery contributes to development of eye in Drosophila

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1 Department of Cell Biology, Institute for Virus Research, Kyoto University, Sakyo-ku, 606-8507 Kyoto, Japan
Front. Biosci. (Landmark Ed) 2018, 23(3), 506–511;
Published: 1 January 2018

Chromosomal DNA replication machinery is essential for growth of all cells in all organs in multicellular organisms. Its knockdown in several tissues of Drosophila led to rough eye phenotype and the loss of bristles in the eye. These results show that the DNA replication machinery contributes to the body development independent of growth.

DNA replication
Tissue specific RNAi-knockwown
Gene Rough Eye
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