DNA replication machinery contributes to development of eye in Drosophila

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Article

Hidetsugu Kohzaki^1,*, Yota Murakami¹

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¹ Department of Cell Biology, Institute for Virus Research, Kyoto University, Sakyo-ku, 606-8507 Kyoto, Japan

Front. Biosci. (Landmark Ed) 2018, 23(3), 506–511; https://doi.org/10.2741/4602

Published: 1 January 2018

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Abstract

Chromosomal DNA replication machinery is essential for growth of all cells in all organs in multicellular organisms. Its knockdown in several tissues of Drosophila led to rough eye phenotype and the loss of bristles in the eye. These results show that the DNA replication machinery contributes to the body development independent of growth.

Keywords

DNA replication

Tissue specific RNAi-knockwown

Drosophila

Gene Rough Eye

Bristle

Development

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