IMR Press / FBL / Volume 19 / Issue 1 / DOI: 10.2741/4197

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review
Dyes and stains: from molecular structure to histological application
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1 Department of Genetics and Complex Diseases, Harvard School of Public Health, Boston, Massachusetts, USA
2 Chemistry Department-INQUISUR, National University of South- CONICET, Alem Av. 1253, (8000) Bahia Blanca, Argentina
Academic Editor:Paula V. Messina
Front. Biosci. (Landmark Ed) 2014, 19(1), 91–112;
Published: 1 January 2014
(This article belongs to the Special Issue Bioorganic and biophysical chemistry: from basics to applications)

In the present review, the chemistry of dyes as well as the interaction mechanisms between tissue and dye has been detailed, and also some of the key factors affecting the selectivity of dyes by certain cellular structures have been mentioned. Moreover, due to the relevance that histological stains have acquired in biomedical research, some of the most common stains have been described, pointing out previous and current applications in basic and applied research.

Staining Mechanism
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