IMR Press / FBL / Volume 18 / Issue 4 / DOI: 10.2741/4172

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review

Endothelial progenitor cells and atherosclerosis

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1 Department of Cardiology, the 8th Renmin hospital, Shanghai, No.8 Cao Bao Road,Shanghai, 200235, China
Academic Editor:Xinyu Wang
Front. Biosci. (Landmark Ed) 2013, 18(4), 1194–1201; https://doi.org/10.2741/4172
Published: 1 June 2013
Abstract

Atherosclerosis is due to inflammation and endothelial dysfunction and damage caused by a variety of factors. Dysfunction of endothelial progenitor cells (EPCs) that differentiate into mature endothelial cell contributes to the development of atherosclerosis. Both the number and functionality of EPCs are regulated, particularly in vascular repair. Further elucidation of the role of EPCs in atherosclerosis could potentially enable the development of novel strategies for prevention and treatment of pathological changes in atherosclerosis.

Keywords
Endothelial progenitor cells
PI3K
SDF1alfa
Review
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