IMR Press / FBL / Volume 17 / Issue 5 / DOI: 10.2741/4016

Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Article
Nanotechnology in stem cells research: advances and applications
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1 DiponEd BioIntelligence LLP, 318, Daddy's garden, Kamasandra, Bangalore 560100, India,
2 Integrative Regenerative, Medicine (IGEN) Centre, Department of Clinical and Experimental Medicine, Linkoping University, 58185 Linkoping, Sweden
3 Ottawa Health Research Institute and Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, Ontario K1H 8L6, Canada
4 Faculty of Health Sciences, Department of Cardiovascular Medicine, Linkoping University, 58185 Linkoping, Sweden
Front. Biosci. (Landmark Ed) 2012, 17(5), 1747–1760; https://doi.org/10.2741/4016
Published: 1 January 2012
Abstract

Human beings suffer from a myriad of disorders caused by biochemical or biophysical alteration of physiological systems leading to organ failure. For a number of these conditions, stem cells and their enormous reparative potential may be the last hope for restoring function to these failing organ or tissue systems. To harness the potential of stem cells for biotherapeutic applications, we need to work at the size scale of molecules and processes that govern stem cells fate. Nanotechnology provides us with such capacity. Therefore, effective amalgamation of nanotechnology and stem cells - medical nanoscience or nanomedicine - offers immense benefits to the human race. The aim of this paper is to discuss the role and importance of nanotechnology in stem cell research by focusing on several important areas such as stem cell visualization and imaging, genetic modifications and reprogramming by gene delivery systems, creating stem cell niche, and similar therapeutic applications.

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