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Article
Biomolecular studies by circular dichroism
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Chemistry Department, INQUISUR, National University of South- CONICET, Alem Av 1253, 8000 Bahia Blanca, Argentina. veronica.dodero@uns.edu.ar
Academic Editor:Paula V. Messina
Front. Biosci. (Landmark Ed) 2011, 16(1), 61–73;
https://doi.org/10.2741/3676
Published: 1 January 2011
(This article belongs to the Special Issue Bioorganic and biophysical chemistry: from basics to applications)
Abstract
In this review, we shall outline the basic principles of circular dichroism (CD) indicating the types of structural information relevant to the study of biomolecules, such as proteins or DNA. We are mainly interested to show the utility of this technique to study protein-ligand, DNA-ligand and protein-DNA interactions.