Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.
The bottom-up construction and operation of machines and motors of molecular size is a topic of great interest in nanoscience, and a fascinating challenge of nanotechnology. The problem of the energy supply to make molecular machines work is of the greatest importance. Research in the last ten years has demonstrated that light energy can be used to power artificial nanomachines by exploiting photochemical processes in appropriately designed systems. More recently, it has become clear that under many aspects light is the best choice to power molecular machines; for example, systems that show autonomous operation and do not generate waste products can be obtained. This review is intended to discuss the design principles at the basis of light-driven artificial nanomachines, and provide an up-to-date overview on the prototype systems that have been developed.