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Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.
Volume 13 Issue 13 2008
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- Open Access Article
The Arabidopsis checkpoint protein Bub3.1 is essential for gametophyte development
Inna Lermontova, Joerg Fuchs, Ingo SchubertFront. Biosci. (Landmark Ed) 2008, 13(13), 5202–5211; https://doi.org/10.2741/3076(This article belongs to the Special Issue Kinetochore and spindle checkpoint)26Download14Citations18Views - Open Access ArticleGlycosylation is crucial for stability of tumour and cancer stem cell antigen EpCAMMarkus Munz, Karin Fellinger, Tanja Hofmann, Barbel Schmitt, Olivier GiresFront. Biosci. (Landmark Ed) 2008, 13(13), 5195–5201; https://doi.org/10.2741/3075(This article belongs to the Special Issue EpCAM, the revival of a long-known tumor-associated antigen)43Download42Citations43Views
- Open Access ArticleThe implication of proinflammatory cytokines in type 2 diabetesChristopher B. Guest, Min J. Park, Daniel R. Johnson, Gregory G. FreundFront. Biosci. (Landmark Ed) 2008, 13(13), 5187–5194; https://doi.org/10.2741/3074(This article belongs to the Special Issue New therapeutic approaches for type 2 diabetes)31Download58Citations20Views
- Open Access ArticleNovel actions of tissue-type plasminogen activator in chronic kidney diseaseKebin Hu, Wendy M. Mars, Youhua LiuFront. Biosci. (Landmark Ed) 2008, 13(13), 5174–5186; https://doi.org/10.2741/3073(This article belongs to the Special Issue New insights into the pathogenesis and therapeutics of renal fibrosis)9Download28Citations3Views
- Open Access ArticleBone marrow-derived progenitor cells and renal fibrosisVolha Ninichuk, Hans-Joachim AndersFront. Biosci. (Landmark Ed) 2008, 13(13), 5163–5173; https://doi.org/10.2741/3072(This article belongs to the Special Issue New insights into the pathogenesis and therapeutics of renal fibrosis)4Download7Citations5Views
- Open Access Article
Genetic background in apolipoprotein A-I and cystathionine β-synthase deficiency
Ricardo Carnicer, Mario A. Guzman, Sergio Acin, Joaquin C. Surra, ... Jesus OsadaFront. Biosci. (Landmark Ed) 2008, 13(13), 5155–5162; https://doi.org/10.2741/30713Download3Citations2Views - Open Access ArticleResistance mechanisms to cancer chemotherapyKelly Marie Redmond, Timothy Richard Wilson, Patrick Gerard Johnston, Daniel Broderick LongleyFront. Biosci. (Landmark Ed) 2008, 13(13), 5138–5154; https://doi.org/10.2741/3070(This article belongs to the Special Issue Cancer progression)43Download83Citations87Views
- Open Access ArticleThe neuroprotective mechanism of action of the multimodal drug ladostigilOrly Weinreb, Tamar Amit, Orit Bar-Am, Merav Yogev-Falach, Moussa B.H. YoudimFront. Biosci. (Landmark Ed) 2008, 13(13), 5131–5137; https://doi.org/10.2741/3069(This article belongs to the Special Issue Molecular biology in clinical practice)11Download27Citations11Views
- Open Access ArticleConverging roles for sphingolipids and cell stress in the progression of neuro-AIDSNorman J. Haughey, Joesph Steiner, Avindra Nath, Justin C. McArthur, ... Ratnam BandaruFront. Biosci. (Landmark Ed) 2008, 13(13), 5120–5130; https://doi.org/10.2741/3068(This article belongs to the Special Issue Molecular basis of neuronal dysfunction in AIDS)8Download20Citations5Views
- Open Access ArticleNew insights in drug development for the non-small cell lung cancer therapyCesare Gridelli, Antonio Rossi, Paolo Maione, Carmine Ferrara, ... Giuseppe ColantuoniFront. Biosci. (Landmark Ed) 2008, 13(13), 5108–5119; https://doi.org/10.2741/3067(This article belongs to the Special Issue Adenylate cyclasecAMP axis and cell growth)2Download3Citations2Views
- Open Access Article
TNF: A master switch for inflammation to cancer
Gautam Sethi, Bokyung Sung, Bharat B. AggarwalFront. Biosci. (Landmark Ed) 2008, 13(13), 5094–5107; https://doi.org/10.2741/3066(This article belongs to the Special Issue Molecular strategies to enhance the anticancer activity of TNF)111Download278Citations243Views - Open Access ArticleThe genetics of malignant melanomaJesus Lomas, Pilar Martin-Duque, Mar Pons, Miguel QuintanillaFront. Biosci. (Landmark Ed) 2008, 13(13), 5071–5093; https://doi.org/10.2741/3065(This article belongs to the Special Issue Genetics and repair in cancer)7Download20Citations5Views
- Open Access ArticleOxidative stress in vascular senescence: lessons from successfully aging speciesZoltan Ungvari, Rochelle Buffenstein, Steven N. Austad, Andrej Podlutsky, ... Anna CsiszarFront. Biosci. (Landmark Ed) 2008, 13(13), 5056–5070; https://doi.org/10.2741/3064(This article belongs to the Special Issue Nitric oxide, superoxide and peroxynitrite in cardiovascular diseases)21Download61Citations13Views
- Open Access ArticleEpCAM in morphogenesisMonika Trzpis, Edwin Bremer, Pamela M.J. McLaughlin, Lou F.M.H. de Leij, Martin C. HarmsenFront. Biosci. (Landmark Ed) 2008, 13(13), 5050–5055; https://doi.org/10.2741/3063(This article belongs to the Special Issue EpCAM, the revival of a long-known tumor-associated antigen)13Download18Citations10Views
- Open Access ArticleEpCAM-targeted induction of apoptosisEdwin Bremer, Wijnand HelfrichFront. Biosci. (Landmark Ed) 2008, 13(13), 5042–5049; https://doi.org/10.2741/3062(This article belongs to the Special Issue EpCAM, the revival of a long-known tumor-associated antigen)10Download3Views
- Open Access ArticleMitochondrial mechanisms of sepsis-induced organ failureMatthew C Exline, Elliot D CrouserFront. Biosci. (Landmark Ed) 2008, 13(13), 5030–5041;(This article belongs to the Special Issue Molecular mechanisms of sepsis)4Download3Views
- Open Access ArticleThe multiple checkpoint functions of CHK1 and CHK2 in maintenance of genome stabilityYue Chen, Randy Y.C. PoonFront. Biosci. (Landmark Ed) 2008, 13(13), 5016–5029;(This article belongs to the Special Issue Genome instability and carcinogenesis)18Download3Views
- Open Access ArticleTemporal regulation of adenovirus major late alternative RNA splicingGoran AkusjarviFront. Biosci. (Landmark Ed) 2008, 13(13), 5006–5015; https://doi.org/10.2741/3059(This article belongs to the Special Issue Protein-RNA interactions in viral RNA processing)20Download40Citations9Views
- Open Access ArticleNovel aspects of the renin-angiotensin-aldosterone-systemGunter WolfFront. Biosci. (Landmark Ed) 2008, 13(13), 4993–5005; https://doi.org/10.2741/3058(This article belongs to the Special Issue New insights into the pathogenesis and therapeutics of renal fibrosis)4Download30Citations10Views
- Open Access ArticleSmad7 as a therapeutic agent for chronic kidney diseasesHui Yao LanFront. Biosci. (Landmark Ed) 2008, 13(13), 4984–4992; https://doi.org/10.2741/3057(This article belongs to the Special Issue New insights into the pathogenesis and therapeutics of renal fibrosis)12Download88Citations12Views
- Open Access ArticleCochlear molecules and hereditary deafnessDenise Yan, Xue-Zhong LiuFront. Biosci. (Landmark Ed) 2008, 13(13), 4972–4983; https://doi.org/10.2741/3056(This article belongs to the Special Issue Genetic and molecular biological basis for gearing and deafness)13Download32Citations13Views
- Open Access ArticleKnock-out mouse models of proprotein convertases: unique functions or redundancy?John W.M. Creemers, Abdel-Majid KhatibFront. Biosci. (Landmark Ed) 2008, 13(13), 4960–4971; https://doi.org/10.2741/3055(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)42Download69Citations15Views
- Open Access ArticleImmunostimulatory virotherapy using recombinant Sendai virus as a new cancer therapeutic regimenYoshikazu Yonemitsu, Yasuji Ueda, Hiroaki Kinoh, Mamoru HasegawaFront. Biosci. (Landmark Ed) 2008, 13(13), 4953–4959; https://doi.org/10.2741/3054(This article belongs to the Special Issue Current gene therapy for cancer)2Download6Citations9Views
- Open Access Article
The SH3 domain- a family of versatile peptide- and protein-recognition module
Tomonori Kaneko, Lei Li, Shawn S.-C. LiFront. Biosci. (Landmark Ed) 2008, 13(13), 4938–4952; https://doi.org/10.2741/3053(This article belongs to the Special Issue Short function motifs in proteins)98Download137Citations58Views - Open Access ArticleArterial remodeling in vascular disease: a key role for hyaluronan and versicanThomas N. WightFront. Biosci. (Landmark Ed) 2008, 13(13), 4933–4937; https://doi.org/10.2741/3052(This article belongs to the Special Issue Advances in cerebrovascular disease pathobiology, biomarkers and treatment)11Download66Citations11Views
- Open Access ArticleProtein tyrosine phosphatases in the JAK/STAT pathwayDan Xu, Cheng-Kui QuFront. Biosci. (Landmark Ed) 2008, 13(13), 4925–4932; https://doi.org/10.2741/3051(This article belongs to the Special Issue JAKSTAT signaling in hematopoiesis)45Download184Citations132Views
- Open Access ArticleInfluenza vaccinesRichard John Webby, Matthew Robert SandbulteFront. Biosci. (Landmark Ed) 2008, 13(13), 4912–4924; https://doi.org/10.2741/3050(This article belongs to the Special Issue Harnessing immune potential by vaccination)10Download9Citations20Views
- Open Access ArticleTest systems for measuring ocular parameters and visual function in miceFrank SchaeffelFront. Biosci. (Landmark Ed) 2008, 13(13), 4904–4911; https://doi.org/10.2741/3049(This article belongs to the Special Issue Genetics of vision and cognition)24Download16Citations23Views
- Open Access ArticleSelectivity and invariance for visual object perceptionMatias J. Ison, Rodrigo Quian QuirogaFront. Biosci. (Landmark Ed) 2008, 13(13), 4889–4903; https://doi.org/10.2741/3048(This article belongs to the Special Issue Genetics of vision and cognition)9Download9Citations5Views
- Open Access ArticleMethods and protocols for the assessment of protein allergenicity and cross-reactivityJoo Chuan Tong, Martti Tapani TammiFront. Biosci. (Landmark Ed) 2008, 13(13), 4882–4888; https://doi.org/10.2741/3047(This article belongs to the Special Issue Molecular biology in clinical practice)2Download5Citations4Views
- Open Access ArticleThe role of programmed-1 ribosomal frameshifting in coronavirus propagationEwan P. Plant, Jonathan D. DinmanFront. Biosci. (Landmark Ed) 2008, 13(13), 4873–4881; https://doi.org/10.2741/3046(This article belongs to the Special Issue Innate immunity and protein synthesis)34Download66Citations111Views
- Open Access ArticleThe role of chemokines during herpes simplex virus-1 infectionTodd R. Wuest, Daniel J. J. CarrFront. Biosci. (Landmark Ed) 2008, 13(13), 4862–4872; https://doi.org/10.2741/3045(This article belongs to the Special Issue Neurotropic virus infections and the host immune response)7Download39Citations8Views
- Open Access Article
B lymphocytes — chief players and therapeutic targets in autoimmune diseases
Moncef ZoualiFront. Biosci. (Landmark Ed) 2008, 13(13), 4852–4861; https://doi.org/10.2741/3044(This article belongs to the Special Issue An update on the pathogenesis of immune dysregulation in autoimmunity)4Download22Citations13Views - Open Access ArticleRecent acquisitions on the genetic basis of autoimmune diseaseNatasha J. Hill, Cecile King, Malin Flodstrom-TullbergFront. Biosci. (Landmark Ed) 2008, 13(13), 4838–4851; https://doi.org/10.2741/3043(This article belongs to the Special Issue An update on the pathogenesis of immune dysregulation in autoimmunity)7Download8Citations142Views
- Open Access ArticleImmune regulation by invariant NKT cells in autoimmunityFrancesca Ronchi, Marika FalconeFront. Biosci. (Landmark Ed) 2008, 13(13), 4827–4837; https://doi.org/10.2741/3042(This article belongs to the Special Issue An update on the pathogenesis of immune dysregulation in autoimmunity)4Download22Citations9Views
- Open Access ArticleRole of Toll like receptor-activated dendritic cells in the development of autoimmunityFrancesca Granucci, Ivan ZanoniFront. Biosci. (Landmark Ed) 2008, 13(13), 4817–4826; https://doi.org/10.2741/3041(This article belongs to the Special Issue An update on the pathogenesis of immune dysregulation in autoimmunity)1Download9Citations4Views
- Open Access ArticleThe heterogeneity of diabetic neuropathyAnders A.F. SimaFront. Biosci. (Landmark Ed) 2008, 13(13), 4809–4816; https://doi.org/10.2741/3040(This article belongs to the Special Issue Insulin and insulin-like growth factor-1 signalings in neuronal cells)5Download9Citations4Views