Frontiers in Bioscience-Landmark (FBL) is published by IMR Press from Volume 26 Issue 5 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Volume 13 Issue 13 2008

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Open Access Article

The Arabidopsis checkpoint protein Bub3.1 is essential for gametophyte development

Inna Lermontova, Joerg Fuchs, Ingo Schubert

Front. Biosci. (Landmark Ed) 2008, 13(13), 5202–5211; https://doi.org/10.2741/3076

(This article belongs to the Special Issue Kinetochore and spindle checkpoint)

Abstract PDF(636.05KB)

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14

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Open Access Article

Glycosylation is crucial for stability of tumour and cancer stem cell antigen EpCAM

Markus Munz, Karin Fellinger, Tanja Hofmann, Barbel Schmitt, Olivier Gires

Front. Biosci. (Landmark Ed) 2008, 13(13), 5195–5201; https://doi.org/10.2741/3075

(This article belongs to the Special Issue EpCAM, the revival of a long-known tumor-associated antigen)

Abstract PDF(375.32KB)

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42

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43

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Open Access Article

The implication of proinflammatory cytokines in type 2 diabetes

Christopher B. Guest, Min J. Park, Daniel R. Johnson, Gregory G. Freund

Front. Biosci. (Landmark Ed) 2008, 13(13), 5187–5194; https://doi.org/10.2741/3074

(This article belongs to the Special Issue New therapeutic approaches for type 2 diabetes)

Abstract PDF(218.72KB)

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58

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20

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Open Access Article

Novel actions of tissue-type plasminogen activator in chronic kidney disease

Kebin Hu, Wendy M. Mars, Youhua Liu

Front. Biosci. (Landmark Ed) 2008, 13(13), 5174–5186; https://doi.org/10.2741/3073

(This article belongs to the Special Issue New insights into the pathogenesis and therapeutics of renal fibrosis)

Abstract PDF(427.07KB)

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28

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Open Access Article

Bone marrow-derived progenitor cells and renal fibrosis

Volha Ninichuk, Hans-Joachim Anders

Front. Biosci. (Landmark Ed) 2008, 13(13), 5163–5173; https://doi.org/10.2741/3072

(This article belongs to the Special Issue New insights into the pathogenesis and therapeutics of renal fibrosis)

Abstract PDF(2.19MB)

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7

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5

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Open Access Article

Genetic background in apolipoprotein A-I and cystathionine β-synthase deficiency

Ricardo Carnicer, Mario A. Guzman, Sergio Acin, Joaquin C. Surra, ... Jesus Osada

Front. Biosci. (Landmark Ed) 2008, 13(13), 5155–5162; https://doi.org/10.2741/3071

Abstract PDF(291.35KB)

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3

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2

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Open Access Article

Resistance mechanisms to cancer chemotherapy

Kelly Marie Redmond, Timothy Richard Wilson, Patrick Gerard Johnston, Daniel Broderick Longley

Front. Biosci. (Landmark Ed) 2008, 13(13), 5138–5154; https://doi.org/10.2741/3070

(This article belongs to the Special Issue Cancer progression)

Abstract PDF(634.71KB)

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83

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87

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Open Access Article

The neuroprotective mechanism of action of the multimodal drug ladostigil

Orly Weinreb, Tamar Amit, Orit Bar-Am, Merav Yogev-Falach, Moussa B.H. Youdim

Front. Biosci. (Landmark Ed) 2008, 13(13), 5131–5137; https://doi.org/10.2741/3069

(This article belongs to the Special Issue Molecular biology in clinical practice)

Abstract PDF(249.10KB)

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27

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11

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Open Access Article

Converging roles for sphingolipids and cell stress in the progression of neuro-AIDS

Norman J. Haughey, Joesph Steiner, Avindra Nath, Justin C. McArthur, ... Ratnam Bandaru

Front. Biosci. (Landmark Ed) 2008, 13(13), 5120–5130; https://doi.org/10.2741/3068

(This article belongs to the Special Issue Molecular basis of neuronal dysfunction in AIDS)

Abstract PDF(374.35KB)

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20

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5

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Open Access Article

New insights in drug development for the non-small cell lung cancer therapy

Cesare Gridelli, Antonio Rossi, Paolo Maione, Carmine Ferrara, ... Giuseppe Colantuoni

Front. Biosci. (Landmark Ed) 2008, 13(13), 5108–5119; https://doi.org/10.2741/3067

(This article belongs to the Special Issue Adenylate cyclasecAMP axis and cell growth)

Abstract PDF(209.68KB)

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3

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2

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Open Access Article

TNF: A master switch for inflammation to cancer

Gautam Sethi, Bokyung Sung, Bharat B. Aggarwal

Front. Biosci. (Landmark Ed) 2008, 13(13), 5094–5107; https://doi.org/10.2741/3066

(This article belongs to the Special Issue Molecular strategies to enhance the anticancer activity of TNF)

Abstract PDF(606.06KB)

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278

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243

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Open Access Article

The genetics of malignant melanoma

Jesus Lomas, Pilar Martin-Duque, Mar Pons, Miguel Quintanilla

Front. Biosci. (Landmark Ed) 2008, 13(13), 5071–5093; https://doi.org/10.2741/3065

(This article belongs to the Special Issue Genetics and repair in cancer)

Abstract PDF(562.90KB)

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20

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5

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Open Access Article

Oxidative stress in vascular senescence: lessons from successfully aging species

Zoltan Ungvari, Rochelle Buffenstein, Steven N. Austad, Andrej Podlutsky, ... Anna Csiszar

Front. Biosci. (Landmark Ed) 2008, 13(13), 5056–5070; https://doi.org/10.2741/3064

(This article belongs to the Special Issue Nitric oxide, superoxide and peroxynitrite in cardiovascular diseases)

Abstract PDF(1.10MB)

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61

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13

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Open Access Article

EpCAM in morphogenesis

Monika Trzpis, Edwin Bremer, Pamela M.J. McLaughlin, Lou F.M.H. de Leij, Martin C. Harmsen

Front. Biosci. (Landmark Ed) 2008, 13(13), 5050–5055; https://doi.org/10.2741/3063

(This article belongs to the Special Issue EpCAM, the revival of a long-known tumor-associated antigen)

Abstract PDF(155.22KB)

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18

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10

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Open Access Article

EpCAM-targeted induction of apoptosis

Edwin Bremer, Wijnand Helfrich

Front. Biosci. (Landmark Ed) 2008, 13(13), 5042–5049; https://doi.org/10.2741/3062

(This article belongs to the Special Issue EpCAM, the revival of a long-known tumor-associated antigen)

Abstract PDF(303.91KB)

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3

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Open Access Article

Mitochondrial mechanisms of sepsis-induced organ failure

Matthew C Exline, Elliot D Crouser

Front. Biosci. (Landmark Ed) 2008, 13(13), 5030–5041;

(This article belongs to the Special Issue Molecular mechanisms of sepsis)

Abstract PDF(298.54KB)

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3

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Open Access Article

The multiple checkpoint functions of CHK1 and CHK2 in maintenance of genome stability

Yue Chen, Randy Y.C. Poon

Front. Biosci. (Landmark Ed) 2008, 13(13), 5016–5029;

(This article belongs to the Special Issue Genome instability and carcinogenesis)

Abstract PDF(290.86KB)

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3

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Open Access Article

Temporal regulation of adenovirus major late alternative RNA splicing

Goran Akusjarvi

Front. Biosci. (Landmark Ed) 2008, 13(13), 5006–5015; https://doi.org/10.2741/3059

(This article belongs to the Special Issue Protein-RNA interactions in viral RNA processing)

Abstract PDF(343.35KB)

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40

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9

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Open Access Article

Novel aspects of the renin-angiotensin-aldosterone-system

Gunter Wolf

Front. Biosci. (Landmark Ed) 2008, 13(13), 4993–5005; https://doi.org/10.2741/3058

(This article belongs to the Special Issue New insights into the pathogenesis and therapeutics of renal fibrosis)

Abstract PDF(260.81KB)

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30

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10

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Open Access Article

Smad7 as a therapeutic agent for chronic kidney diseases

Hui Yao Lan

Front. Biosci. (Landmark Ed) 2008, 13(13), 4984–4992; https://doi.org/10.2741/3057

(This article belongs to the Special Issue New insights into the pathogenesis and therapeutics of renal fibrosis)

Abstract PDF(397.43KB)

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88

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12

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Open Access Article

Cochlear molecules and hereditary deafness

Denise Yan, Xue-Zhong Liu

Front. Biosci. (Landmark Ed) 2008, 13(13), 4972–4983; https://doi.org/10.2741/3056

(This article belongs to the Special Issue Genetic and molecular biological basis for gearing and deafness)

Abstract PDF(208.89KB)

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32

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13

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Open Access Article

Knock-out mouse models of proprotein convertases: unique functions or redundancy?

John W.M. Creemers, Abdel-Majid Khatib

Front. Biosci. (Landmark Ed) 2008, 13(13), 4960–4971; https://doi.org/10.2741/3055

(This article belongs to the Special Issue Genetically-modified animals as research models in development and disease)

Abstract PDF(558.53KB)

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69

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15

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Open Access Article

Immunostimulatory virotherapy using recombinant Sendai virus as a new cancer therapeutic regimen

Yoshikazu Yonemitsu, Yasuji Ueda, Hiroaki Kinoh, Mamoru Hasegawa

Front. Biosci. (Landmark Ed) 2008, 13(13), 4953–4959; https://doi.org/10.2741/3054

(This article belongs to the Special Issue Current gene therapy for cancer)

Abstract PDF(1.17MB)

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6

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9

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Open Access Article

The SH3 domain- a family of versatile peptide- and protein-recognition module

Tomonori Kaneko, Lei Li, Shawn S.-C. Li

Front. Biosci. (Landmark Ed) 2008, 13(13), 4938–4952; https://doi.org/10.2741/3053

(This article belongs to the Special Issue Short function motifs in proteins)

Abstract PDF(896.19KB)

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137

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58

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Open Access Article

Arterial remodeling in vascular disease: a key role for hyaluronan and versican

Thomas N. Wight

Front. Biosci. (Landmark Ed) 2008, 13(13), 4933–4937; https://doi.org/10.2741/3052

(This article belongs to the Special Issue Advances in cerebrovascular disease pathobiology, biomarkers and treatment)

Abstract PDF(326.07KB)

11

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66

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11

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Open Access Article

Protein tyrosine phosphatases in the JAK/STAT pathway

Dan Xu, Cheng-Kui Qu

Front. Biosci. (Landmark Ed) 2008, 13(13), 4925–4932; https://doi.org/10.2741/3051

(This article belongs to the Special Issue JAKSTAT signaling in hematopoiesis)

Abstract PDF(175.15KB)

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184

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132

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Open Access Article

Influenza vaccines

Richard John Webby, Matthew Robert Sandbulte

Front. Biosci. (Landmark Ed) 2008, 13(13), 4912–4924; https://doi.org/10.2741/3050

(This article belongs to the Special Issue Harnessing immune potential by vaccination)

Abstract PDF(587.17KB)

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9

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20

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Open Access Article

Test systems for measuring ocular parameters and visual function in mice

Frank Schaeffel

Front. Biosci. (Landmark Ed) 2008, 13(13), 4904–4911; https://doi.org/10.2741/3049

(This article belongs to the Special Issue Genetics of vision and cognition)

Abstract PDF(485.61KB)

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16

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23

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Open Access Article

Selectivity and invariance for visual object perception

Matias J. Ison, Rodrigo Quian Quiroga

Front. Biosci. (Landmark Ed) 2008, 13(13), 4889–4903; https://doi.org/10.2741/3048

(This article belongs to the Special Issue Genetics of vision and cognition)

Abstract PDF(372.22KB)

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9

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5

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Open Access Article

Methods and protocols for the assessment of protein allergenicity and cross-reactivity

Joo Chuan Tong, Martti Tapani Tammi

Front. Biosci. (Landmark Ed) 2008, 13(13), 4882–4888; https://doi.org/10.2741/3047

(This article belongs to the Special Issue Molecular biology in clinical practice)

Abstract PDF(164.90KB)

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5

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4

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Open Access Article

The role of programmed-1 ribosomal frameshifting in coronavirus propagation

Ewan P. Plant, Jonathan D. Dinman

Front. Biosci. (Landmark Ed) 2008, 13(13), 4873–4881; https://doi.org/10.2741/3046

(This article belongs to the Special Issue Innate immunity and protein synthesis)

Abstract PDF(507.54KB)

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66

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111

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Open Access Article

The role of chemokines during herpes simplex virus-1 infection

Todd R. Wuest, Daniel J. J. Carr

Front. Biosci. (Landmark Ed) 2008, 13(13), 4862–4872; https://doi.org/10.2741/3045

(This article belongs to the Special Issue Neurotropic virus infections and the host immune response)

Abstract PDF(241.57KB)

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39

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8

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Open Access Article

B lymphocytes — chief players and therapeutic targets in autoimmune diseases

Moncef Zouali

Front. Biosci. (Landmark Ed) 2008, 13(13), 4852–4861; https://doi.org/10.2741/3044

(This article belongs to the Special Issue An update on the pathogenesis of immune dysregulation in autoimmunity)

Abstract PDF(187.90KB)

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22

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13

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Open Access Article

Recent acquisitions on the genetic basis of autoimmune disease

Natasha J. Hill, Cecile King, Malin Flodstrom-Tullberg

Front. Biosci. (Landmark Ed) 2008, 13(13), 4838–4851; https://doi.org/10.2741/3043

(This article belongs to the Special Issue An update on the pathogenesis of immune dysregulation in autoimmunity)

Abstract PDF(267.51KB)

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8

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142

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Open Access Article

Immune regulation by invariant NKT cells in autoimmunity

Francesca Ronchi, Marika Falcone

Front. Biosci. (Landmark Ed) 2008, 13(13), 4827–4837; https://doi.org/10.2741/3042

(This article belongs to the Special Issue An update on the pathogenesis of immune dysregulation in autoimmunity)

Abstract PDF(356.46KB)

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22

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9

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Open Access Article

Role of Toll like receptor-activated dendritic cells in the development of autoimmunity

Francesca Granucci, Ivan Zanoni

Front. Biosci. (Landmark Ed) 2008, 13(13), 4817–4826; https://doi.org/10.2741/3041

(This article belongs to the Special Issue An update on the pathogenesis of immune dysregulation in autoimmunity)

Abstract PDF(387.81KB)

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9

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Open Access Article

The heterogeneity of diabetic neuropathy

Anders A.F. Sima

Front. Biosci. (Landmark Ed) 2008, 13(13), 4809–4816; https://doi.org/10.2741/3040

(This article belongs to the Special Issue Insulin and insulin-like growth factor-1 signalings in neuronal cells)

Abstract PDF(636.92KB)

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