Role of p14ARF alterations in endometrial tumorigenesis: a mini-review

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

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Role of p14ARF alterations in endometrial tumorigenesis: a mini-review

Andrzej Semczuk^1,*, Klaudiusz Cieplinski², Atanas Ignatov³, Piotr Olcha¹, Tomasz Rechberger¹

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¹ 2nd Department of Gynecology, Lublin Medical University, Lublin, Poland

² Department of Obstetrics and Gynecology, Municipal Hospital in Plock, Plock, Poland

³ Department of Obstetrics and Gynecology, Otto-von-Guericke University, Magdeburg, Germany

*Author to whom correspondence should be addressed.

Academic Editor: Anna Czarnecka

Front. Biosci. (Elite Ed) 2012, 4(7), 2457–2463; https://doi.org/10.2741/E557

Published: 1 June 2012

(This article belongs to the Special Issue Frontiers in molecular medicine)

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Abstract

In the current mini-review, we present a short overview of genetic as well as immunohistochemical p14ARF alterations either in primary human endometrial carcinomas (ECs) or in metastatic lesions originated from malignant endometrium. The prognostic utility of p14ARF in uterine malignancies has also been briefly discussed.

Keywords

p14ARF

Endometrial cancer

Patients

Prognosis

Review

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