IMR Press / FBE / Volume 4 / Issue 2 / DOI: 10.2741/e407

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Review

Nutritional issues in heart transplant candidates and recipients

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1 Department of Cardiovascular Surgery and Transplant, Vincenzo Monaldi Hospital, 5 Leonardo Bianchi Street, 80131, Naples, Italy

*Author to whom correspondence should be addressed.

Academic Editor: Fabio Galvano

Front. Biosci. (Elite Ed) 2012, 4(2), 662–668; https://doi.org/10.2741/e407
Published: 1 January 2012
(This article belongs to the Special Issue Dietary approaches to prevent chronic-degenerative diseases)
Abstract

Heart transplant is the golden standard in the management of end-stage heart failure. Recent studies have pointed out the role of nutritional issues in patients evaluated for heart transplant listing. In particular, extremes in body habitus, cachexia and obesity, have been characterized and identified as independent prognostic factors and clinically relevant target for therapeutic interventions. Effects of such conditions exert a prognostic implication well beyond waiting time up to early post transplant setting. Changes in posttransplant clinical conditions and nutritional status have been recently described in their pattern of presentation and implications on weight gain, reversal of preoperative cachexia and early and late morbidity and mortality. New onset diabetes mellitus and metabolic syndrome have been disclosed as relevant clinical conditions in this setting. Implications for tailoring of immunosuppressive therapy and dietary prescription emerged as main stem of long term recipient management. All this issues have been reviewed focusing on the clinical relevance of this growing body of knowledge and emphasizing the role of a multidisciplinary approach for selection and management of heart transplant recipients.

Keywords
Heart Transplant
Waiting List
Outcomes
Obesity
Cachexia
Diabetes
Immunosuppression
Chronic Allograft Vasculopathy
Review
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