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Article
Suppressing allergic immune responses
Hua Huang1,*
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1
Department of Medicine and Integrated Department of Immunology, National Jewish Health, University of Colorado Denver School of Medicine, 1400 Jackson Street, K613e, Denver, CO 80206
*Author to whom correspondence should be addressed.
Front. Biosci. (Elite Ed) 2011, 3(3), 864–870;
https://doi.org/10.2741/E294
Published: 1 June 2011
Abstract
While most studies are devoted to understanding the activation of cytokine gene transcription, few studies have focused on the silencing of cytokine gene transcription. This review will focus on the molecular mechanisms by which Th1-promoting factors downregulate the Il4 gene.
Keywords
Allergy immune responses
IL-4
airway inflammation
Th1-Promoting Factors
Review