IMR Press / FBE / Volume 3 / Issue 2 / DOI: 10.2741/E278

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with Frontiers in Bioscience.

Open Access Article
Recent advances in nano-based electrochemical biosensors: application in diagnosis and monitoring of diseases
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1 Centro de Ciencias Naturais e Humanas, Universidade Federal do ABC, 09210-170 Santo-Andre, Sao Paulo, Brasil
2 Departamento de Quimica, Centro de Ciencias da Natureza, Universidade Federal do Piaui, 64049-550 Teresina, Piaui, Brasil
3 Instituto de Quimica, Universidade Federal de Uberlandia, 38400-902 Uberlandia, Minas Gerais, Brasil
4 Instituto de Genetica e Bioquimica, Universidade Federal de Uberlandia, 38400-902 Uberlandia, Minas Gerais, Brasil
5 Instituto de Ciencia e Tecnologia, Universidade Federal dos Vales do Jequitinhonha e Mucuri, 39100-000 Diamantina, Minas Gerais, Brasil

*Author to whom correspondence should be addressed.

Academic Editor: Aihua Liu

Front. Biosci. (Elite Ed) 2011, 3(2), 663–689; https://doi.org/10.2741/E278
Published: 1 January 2011
(This article belongs to the Special Issue Nano-inspired biosensing and biodetection)
Abstract

Based on biological molecules combined with nanostructured components, the news generations of electrochemical biosensors can employ different transducers (potentiometric, amperometric and impedimetric) converting the chemical information into a measurable amperometric signal. Following this contemporary theme, our main focus in this review is to discuss different methodologies for application in biosensing, whose signal transduction is based on electrochemical principles. We apply a discussion on recent trends involving different nanostructured materials, but without daring to contemplate all nanomaterials incessantly cited in literature, which leads us to believe that this moment is an unprecedented revolution in the preparation of electrochemical biodevices. Besides, some structures of bio-nano interface and different electrochemical biosensors involved in diagnosis systems are also discussed. We outline in several parts of the report how nanoscience technologies are emerging in diagnostic medicine, as well as convergence of electrochemistry and bio-nanoscience. Our hopes for this review are that it can help different categories of researchers to understand the broad application area of electrochemistry and bioelectrochemistry, in order to detecting several types of diseases and biological phenomena.

Keywords
Biosensors
Nanomedicine
Nanoscience
Electrochemistry
Review
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