IMR Press / FBE / Volume 2 / Issue 2 / DOI: 10.2741/E112

Frontiers in Bioscience-Elite (FBE) is published by IMR Press from Volume 13 Issue 2 (2021). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with Frontiers in Bioscience.

Donkey's milk detailed lipid composition
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1 Department of Analytical Chemistry - University of Turin, Italy
2 Neonatal Unit, Department of Paediatric and Adolescence Science, University of Turin, Italy
3 Dept. of Paediatric and Adolescence Science, Regina Margherita Children's Hospital, Turin, Italy
4 CNR-Institute of Science of Food Production, Turin, Italy
5 Biochemical and Clinical Laboratory, San Martino Hospital, Genoa, Italy
6 Department of Biological Chemistry, Medical Chemistry and Molecular Biology, University of Catania, Catania, Italy

*Author to whom correspondence should be addressed.


Front. Biosci. (Elite Ed) 2010, 2(2), 537–546;
Published: 1 January 2010

Donkey's milk (DM) has recently aroused scientific interest, above all among paediatric allergologists. A deeper knowledge of both proteins and fats in donkey's milk is necessary to evaluate the immunological, physiological and nutritional properties. By using the most refined techniques for fatty acids analysis, the paper offers a detailed comparative analysis of the lipid fractions of DM as well as of human and cow milk, also indicating the distribution of fatty-acid moieties among sn-1/3 and sn-2 positions of the glycerol backbone. In DM the position of fatty acids on glycerol backbone, above all of long chain saturated fatty acids, is very similar to that of human milk: this fact, in conjunction with the relatively high contents of medium-chain triglycerides, makes the lipids in DM, through quantitatively reduced, highly bioavailable. The high PUFA n-3 content of donkey's milk, and especially its low n-6/n-3 ratio, acquires particular interest in subjects affected by cow's milk protein allergy. Whole DM might also constitute the basis forformulas suitable for subjects in the first year of life.

Cow’s Milk Protein Allergy
Fatty Acids
Mass Spectrometry
Nutritional Value
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