IMR Press / EJGO / Volume 9 / Issue 2 / pii/1988034

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research

Role of radiotherapy in the management of cervical carcinoma

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1 I Gynaecological Institute, University of Bari, Italy
Eur. J. Gynaecol. Oncol. 1988, 9(2), 163–167;
Published: 10 April 1988

Different therapy schemes related with the stage of tumours are reported, after ge­neral considerations on the topic. We have evaluated various criteria for the choice of methods, pointing out the complications of therapy. Lithium-carbonate action during radiation therapy has been studied, valuing the posi­tive effect on leukopoiesis and the consequent better clinical conditions of the patients in course of treatment. In this study we report our experience with regard to 21 patients affected by cervical neo­plasia, histologically diagnosed. The stages of neoplasia in the 21 patients were so distributed: 10 at stage I B, 8 at stage II A, 3 at stage II B. Treatment consisted of three therapeutical techniques:

1)    application of radium in the cervical canal and in the vaginal fornices; 
2)     surgical procedure; 
3)     application of radium against the vaginal vault. 
In agreement with other Author's results, the histological exam of the surgical specimen con­firmed in different cases the complete absence of neoplastic aspects following the pre-operative radiotherapy. Although our experience is limited, we hold that radio-surgical "sandwich" treatment of cervical carcinoma may represent an excellent therapy in young women and in patients with associated systemic diseases. The follow-up of the 21 patients has excluded up to this day any neoplasia. In this program pre-operative intracavitary radiotherapy is a primary step allowing, in the majo­rity of the cases, the reduction of surgical radicality. In so doL1g, effective therapeutical results associated with a better quality of life are obtained.  


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