European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Advanced uterine sarcoma; response to chemotherapy
A 15 year retrospective study of chemotherapy response to multiple regimens employed in 78 evaluable patients with advanced uterine sarcoma was performed. Single agent activity was noted with doxorubicin, methotrexate, and cisplatin (5-11 % response rate). Effective multigent regimens included cyclosphosphamide, vincristine, doxorubicin, dacarbazine (CYV ADIC) (23% response), cisplatin, and dacarbazine (21 % response) and vincristine, dactinomycin, and cyclophosphamide (VAC) (18% response). There was no difference in response rate among di£ferent histologies. More active agents or combinations are needed.