Chorioangioma is a rare kind of benign placental tumor. Generally, patients have no clinical symptoms if tumors are small. The giant chorioangiomas would trigger multiple complications, which result in adverse outcome of fetus. However, the fetus sudden death caused by the large tumor with no complications was really less reported. We herein present a case of intrauterine fetal death due to a giant placental chorioangioma to remind the clinicians that the treatment should be performed as soon as possible to avoid this kind of tragedy.