A 61-year-old woman was admitted to this hospital with a diagnosis of a poorly differentiated endometrioid carcinoma with myometrial invasion greater than 50 % (IBG3) at MRI. A laparoscopic surgical treatment with peritoneal washing, a type A radical hysterectomy, bilateral salpingo-oophorectomy, and pelvic and para-aortic lymphadenectomy were programmed. Six months later the patient underwent a PET/CT scan that diagnosed a suspected recurrence into the lymph node tissue laterally to the left common iliac artery. Then, the patient underwent a second laparoscopic procedure for dissection of the positive tissue at PET/CT scan on the external site of common iliac artery. At histological examination the dissected two lymph nodes were negative for metastasis and the patient was regularly discharged three days after laparoscopy.