Objective: To investigate the effect of automated breast volume scanner (ABVS) census on the quality of life of the patients with breast hyperplastic nodules < 1 cm. Materials and Methods: From March 2014 to February 2016, 1,366 subjects were screened in the Fourth Hospital of Shijiazhuang. Hamilton Anxiety Scale (HAMA) and Hamilton Rating Scale for Depression (HAMD) were compared between the subjects received ABVS and those received color Doppler ultrasound. Then the 289 patients with breast hyperplastic nodules < 1 cm were divided into groups according to the different clinical manifestations and surgical methods to compare their HAMA and HAMD scores. Results: There were significant differences in HAMA and HAMD scores between the subjects received color Doppler ultrasound and those receiving ABVS examination (p < 0.05). HAMA and HAMD scores were also statistically different (p < 0.05) in terms of the different clinical manifestations and surgical methods. Conclusion: ABVS examination can detect early-stage of hyperplastic nodules more accurately the conventional color Doppler ultrasound and guide the patients for further treatment.