IMR Press / EJGO / Volume 40 / Issue 4 / DOI: 10.12892/ejgo5126.2019
Open Access Editorial
One step nucleic acid amplification (OSNA): one step ahead in gynecological surgical oncology
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1 From the Department of Medical and Surgical Sciences, University Hospital of Modena, Modena, Italy
Eur. J. Gynaecol. Oncol. 2019, 40(4), 519–520; https://doi.org/10.12892/ejgo5126.2019
Revised: 20 March 2019 | Published: 10 August 2019
Abstract

Neoplastic spread to lymph nodes is one of the most important prognostic factors in female cancer and one of the well known TNM classification parameters, together with tumor size and distant metastases. The nodal status is in faet a significant predictor, which supports clinicians to decide on the most appropriate surgical approach and subsequent therapy. The precise intraoperative assessment of sentinel lymph node and eventual metastatic burden is therefore decisive for providing high diagnostic quality and reliable staging. Since methodologies differ across ìnstìtutions, standardization of results is also a challenge. Today, one step nucleic acid amplificatìon (OSNA) meets all these needs.

Keywords
One-step nucleic acid amplification (OSNA)
Sentinel lymph node
Sentinel lymph node biopsy
Vulvar cancer
Gynecological surgical oncology
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