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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Small cell neuroendocrine carcinomas of the uterine cervix: case report
Yi Ding1, †, Hongyan Gao2, †, Shan Meng3, Xia Yuan1, Qing Wang2, Yan Peng4, Jiming Chen5, *
1 Department of Obstetrics & Gynecology, Jintan Hospital Affiliated to Jiangsu University, Jintan, China
2 Department of Obstetrics & Gynecology, the Third Affiliated Hospital of Suzhou University, Changzhou, China
3 Department of Obstetrics & Gynecology, the First Affiliated Hospital of Third Military Medical University, Chongqing, China
4 Department of Pathology, the Third Affiliated Hospital of Suzhou University, Changzhou, China
5 Department of Obstetrics and Gynaecology, the Second Affiliated Hospital of Chongqing Medical University, Chongqing, China
† Contributed equally.
Eur. J. Gynaecol. Oncol. 2018, 39(3), 507–510; https://doi.org/10.12892/ejgo4108.2018
Published: 10 June 2018
Purpose: Small cell neuroendocrine carcinoma (SCNEC) in the cervix is a rare entity of cervical carcinoma associated with invasiveness and poor prognosis. There is limited knowledge of etiology of SCNEC. The diagnosis depends on pathological examination. Various treatment regimes are suggested. Case Report: In this article, the authors present a case of SCNEC. A 33-year-old woman was admitted with complaints of contact vaginal bleeding for one week. Pathological examination showed that synaptophysin (Syn) and CD56 were positive in tumor cells and the case was single cell type SCNEC. For this case, the authors selected TP regime after surgery and achieved better outcome. Conclusion: Combination of surgery, radiotherapy, and chemotherapy is recommended to treat the patients.