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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Rare late mandibular recurrence of uterine leiomyosarcoma: a case report
G. Miolo1, M. Uccello1, D. A. Santeufemia2, G. M. Pes4, A. Buonadonna1, G. Baldino2, F. Dessole3, G. Capobianco3, *
1 Division of Medical Oncology B, Centro di Riferimento Oncologico, National Cancer Institute, Aviano, Italy
2 Medical Oncology Unit, General Hospital, Alghero, Italy
3 Gynecologic and Obstetric Clinic, Department of Surgical, Microsurgical and Medical Sciences, Sassari University, Sassari, Italy
4 Department of Clinical and Experimental Medicine, Sassari, Italy
Eur. J. Gynaecol. Oncol. 2018, 39(1), 146–148; https://doi.org/10.12892/ejgo4164.2018
Published: 10 February 2018
Sarcomas represent 1-2% of all uterine malignancies and leiomyosarcomas (LMSs) are the most common histological subtype, accounting for nearly 30% of all uterine sarcomas. The diagnosis is incidental following routine hysterectomy, and the disease exhibits a high rate of relapse and distant metastases. The most common location for metastasis is the lung, while the finding of bone metastasis in the oral region is exceedingly rare. Here the authors report the case of an exceedingly rare mandibular disease recurrence from a previously uterine LMS refractory to multiple treatments, which was beneficially managed by systemic trabectedin administration. The authors also discuss the features connected with the diagnosis and management of such an uncommon presentation of the metastatic disease.