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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Comparison of four different treatment modalities in Stage IIA cervical cancer: single center experience of 22 years
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1
Tepecik Education and Research Hospital, Department of Gynecologic Oncology, Izmir, Turkey
2
Tepecik Education and Research Hospital, Department of Obstetrics and Gynecology, Izmir, Turkey
Eur. J. Gynaecol. Oncol. 2018, 39(1), 108–111;
https://doi.org/10.12892/ejgo3958.2018
Published: 10 February 2018
Abstract
Objectives: To evaluate the efficacy and the survival rate depending on different treatment modalities in FIGO Stage IIA cervical cancer. Materials and Methods: The authors identified 59 FIGO Stage IIa patients from 844 cervical cancer patients who were treated between January, 1992 and February, 2014. Medical records were retrospectively reviewed and patients were classified according to four different treatment modalities and compared regarding complications, recurrence, and overall survival rates. Results: Fifty-nine (6.99%) of the 844 cervix cancer patients were at FIGO Stage IIA. Fourteen patients received primary radiotherapy (RT), 27 patients primary chemoradiotherapy (CRT), ten patients had radical hysterectomy followed by adjuvant RT, and eight patients had radical hysterectomy followed by adjuvant CRT. Five-year overall survival rates among the primary RT , primary CRT, adjuvant RT after radical hysterectomy (RH), and adjuvant CRT after RH groups were found to be 55.6%, 72.7%, 62.5%, and 71.4% (p = 0.802), respectively and fiveyear disease free survival rates of these groups were found to be 71.4%, 88.9% , 80% , and 87.5% (p = 0.537), respectively. Conclusion: No statistically significant difference was identified regarding the efficacy and the rate of survival among four different treatment modalities in Stage IIa cervical cancer patients.
Keywords
Cervical cancer
Treatment modalities
Radiotherapy
Radical hysterectomy