IMR Press / EJGO / Volume 38 / Issue 6 / DOI: 10.12892/ejgo3669.2017

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
Ovarian serous cystadenofibroma with concomitant sex cord-stromal elements: a case of a relatively common ovarian tumor with an unusual related minor component
Show Less
1 Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, USA
2 Department of Pathology, Abbott Northwestern Hospital, Minneapolis, MN, USA
Eur. J. Gynaecol. Oncol. 2017, 38(6), 960–962;
Published: 10 December 2017

Benign ovarian serous tumors are lesions comprised of benign tubal type epithelium and varying proportions of stromal and cystic components. In rare instances, benign ovarian serous tumors can also contain a minor component of sex cord-stromal elements. The authors describe the case of a 59-year-old postmenopausal woman presenting with a right ovarian mass, that upon resection and examination of permanent sections, was appreciated to predominately be a serous cystadenofibroma. Additionally, there were cords and focal sheets of sex cord-stromal elements, that by immunohistochemical staining, were positive for calretinin and inhibin. The histomorphologic and immunophenotypical features supported that the ovarian tumor was a serous cystadenofibroma with sex cord-stromal elements: this being the second description in the literature to date. While there is a paucity of prognostic data on benign ovarian serous tumors with sex cord-stromal elements, the benign histologic features suggest a favorable outcome for patients, as one would expect with any surgically resected counterpart lesion devoid of sex cord-stromal elements.
Serous cystadenofibroma
Sex cord-stromal elements
Back to top