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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Management of cervical dysplasia in patient with Müllerian anomaly: diagnostic and therapeutic challenges
R. Sparic1, 2, J. Dotlic1, 2, *, J. Kovac2, 3, I. Babovic1, 2, S. Buzadzic<span style="font-size:10px;">1, L. Mirkovic1, 2, L. Nejkovic4, J. Stamenkovic1, 2
1 Clinic for Obstetrics and Gynecology, Clinical Centre of Serbia, Belgrade, Serbia
2 Faculty of Medicine, University of Belgrade, Belgrade, Serbia
3 Center for Radiology and Magnetic Resonance Imaging, Clinical Centre of Serbia, Belgrade, Serbia
4 Clinic for Gynecology and Obstetrics "Narodni Front", Belgrade, Serbia
Eur. J. Gynaecol. Oncol. 2017, 38(3), 469–472; https://doi.org/10.12892/ejgo3550.2017
Published: 10 June 2017
Purpose: The study aim was to report diagnostic and therapeutic challenges in treatment of a patient with cervical dysplasia and congenital uterine anomaly. Case Report: A 53-year-old women with Mullerian anomaly – uterus duplex (bicorporal septate uterus) and Yshaped endocervical canal was referred due to repeated abnormal Pap smears. She underwent endocervical curettage of both canals and the endocervical septum biopsy which revealed presence of cervical intraepithelial neoplasia (CIN) III. Cervical conization was considered technically unfeasible because of abnormal cervical anatomy (lesions deep in the cervical canal on the cervical bifurcation where the cervical wall is the thickest). Classical open abdominal hysterectomy was performed. Patient had two almost equally-sized, symmetrical uterine bodies connected in the isthmico-cervical region, with normal left and obstructed right hemi-vagina. Postoperative histopathological findings confirmed that dysplasia was located in the region where two endocervical canals conjoined. Conclusion: Diagnostic and therapeutic approach to patients with uterine anomalies has to be individualized, based on anomaly type, patient's age, reproductive history, and patient's preferences.