IMR Press / EJGO / Volume 38 / Issue 1 / DOI: 10.12892/ejgo3432.2017

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research
Gestational trophoblastic disease in Campinas, Brazil and persistency predictors
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1 Department of Obstetrics and Gynecology, School of Medical Sciences, State University of Campinas (UNICAMP), Campinas, São Paulo, Brazil
Eur. J. Gynaecol. Oncol. 2017, 38(1), 91–94;
Published: 10 February 2017

Purpose: To determine the prevalence of the gestational trophoblastic disease (GTD) and to evaluate the risk factors for persistence of the disease. Materials and Methods: A retrospective study with 152 women diagnosed with GTD at University of Campinas from 2006 to 2013. Frequencies, average, and standard deviation were evaluated for each variable and an exact Fisher test was utilized to study persistent disease risk factors. Results: The women were on average 25.81 ± 8.02 years old. The most prevalent blood type was O positive (49.6%). The diagnosis of complete mole was found in 64.8%, followed by partial mole in 32%, and choriocarcinoma in 3%. Complete mole developed invasive mole in 12.3%, the same occurred with 7.5% of the partial moles. No significant association was found between age, number of gestations, race, BMI or blood type and persistent mole. Conclusion: The complete mole is the most frequent GTD, and is at high risk for developing malignant forms.
Gestational trophoblastic disease
Persistent gestational trophoblastic disease
Hydatidiform mole
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