IMR Press / EJGO / Volume 37 / Issue 5 / DOI: 10.12892/ejgo3113.2016

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.

Original Research
Risk factors of node metastasis in cervical carcinoma
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1 Women's Hospital, School of Medicine, Zhejiang University, Hangzhou, P.R.China
2 Zhejiang Yiwu Chouzhou Hospital, Yiwu, P.R.China
Eur. J. Gynaecol. Oncol. 2016, 37(5), 662–665; https://doi.org/10.12892/ejgo3113.2016
Published: 10 October 2016
Abstract

Purpose of investigation: To investigate the metastatic risk factors of pelvic lymph nodes in patients with cervical carcinoma in Stage Ia2 and IIa2. Materials and Methods: The clinic pathologic parameters in 337 patients with Stage Ia2-IIa2 cervical carcinoma were retrospectively analyzed. The risk factors for pelvic lymph node metastasis were evaluated by the way of univariate Xstatistic analysis and binary logistic regression analysis. Results: The lymph nodes metastasis rate was 11.87% (40/337). Single variable analysis showed that age, clinical stage, the size of tumor ≥ four cm, depth of stromal invasion ≥ 2/3, lymph-vascular space involvement (LVSI), and parametrial extension were related to the metastasis of lymph nodes. Multivariate analysis showed that the size of tumor, depth of stromal invasion, LVSI, and parametrial extension were independent risk factors. Conclusion: Patients with tumor size ≥ four cm, stromal invasion ≥ 2/3, LVSI, and parametrial extension were at high risk of lymph node metastasis.
Keywords
Cervical cancer
Lymph nodes
Metastasis
Risk factor
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