IMR Press / EJGO / Volume 37 / Issue 4 / DOI: 10.12892/ejgo3201.2016

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
Gynandroblastoma of postmenopausal women: a case report
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1 Department of Obstetrics and Gynecology, Kansai Rosai Hospital, Amagasaki-shi, Hyogo-ken, Japan
2 Department of Clinical Pathology, Itami City Hospital, Itami-shi, Hyogo-ken, Japan
3 Department of Pathology, Kansai Rosai Hospital, Amagasaki-shi, Hyogo-ken, Japan
4 Department of Clinical Pathology, National Hospital Organization Osaka Minami Medical Center, Kawachi-Nagano-shi, Osaka, Japan
Eur. J. Gynaecol. Oncol. 2016, 37(4), 581–583;
Published: 10 August 2016

Gynandroblastoma, an extremely rare ovarian tumour that usually consists of both Sertoli stromal cell and granulosa cell tumours, often produces both androgenic and estrogenic effects. The authors herein report a case of gynandroblastoma with the longest diseasefree period reported to date. A 66-year-old woman without metrorrhagia or hirsutism presented with abdominal pain and slightly elevated serum estradiol levels. Her uterus was enlarged, and endometrial curettage performed to reduce endometrial thickness prior to laparotomy led to a diagnosis of atypical endometrial hyperplasia. She was diagnosed of ovarian tumour. The pathology report revealed that the right ovarian tumour was a "gynandroblastoma". Such lesions are classified as borderline malignant. Postoperative adjuvant therapy was not administered in this case because only a few recurrent or fatal cases have been reported. The lesion was classified as pT1aN0M0 according to Union for International Cancer Control (UICC). The patient is alive and has been disease-free for 77 months post-surgery.
Sex cord
Stromal cell tumours
Granulosa cell tumor
Sertoli cell tumour
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