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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Case Report
Multimodal oncosurgery approach to treat peritoneal carcinomatosis in a patient with occlusive ovarian carcinoma
B. Moldovan1,*, F. Pescaru2, D. Pocreaţă Pocreaţă1, P. Biriş Biriş3, A. Moldovan4, M.E. CăpÎlna CăpÎlna5
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1
General Surgery Department, "Sf.Constantin" Hospital, Braşov, Romania
2
Oncology Department, "Sf.Constantin" Hospital, Braşov, Romania
3
"Regina Maria" Diagnostic and Imagistics Centre, Braşov, Romania
4
Department of Infectious Diseases, "Sf.Constantin" Hospital, Braşov, Romania
5
1st Obstetrics and Gynaecology Clinic, Targu-Mureş, Romania
Eur. J. Gynaecol. Oncol. 2016, 37(2), 251–253;
https://doi.org/10.12892/ejgo2806.2016
Published: 10 April 2016
Abstract
Background: This paper aims to present a "pattern" of oncosurgery solution in a case generally considered unrecoverable: intestinal occlusion in case of ovarian carcinoma and carcinomatosis. Case Report: A 62-year-old female patient with ascites, carcinomatosis, unresectable pelvic tumour, and intestinal obstruction suffered a five-step oncosurgery "model": three surgical interventions overlapping chemotherapy administered via the systemic and intraperitoneal route: Step 1: colostomy and partial omentectomy; Step 2: five courses of systemic chemotherapy supported by granulocyte colony-stimulating factor; Step 3: radical surgery - total hysterectomy, bilateral adnexectomy, pelvic lymphadenectomy, omentectomy, appendectomy, pelvic peritonectomy, and hyperthermic intraperitoneal chemotherapy; Step 4: consolidation systemic chemotherapy consisting of three more similar cycles; Step 5: closure of the colostomy. Nine months after the beginning of treatment, the patient is with no evidence of disease. Conclusions: The association of surgical and oncologic treatment and the use of hyperthermic intraperitoneal chemotherapy (HIPEC) technology can solve some of these complex cases.
Keywords
Peritoneal carcinomatosis
Occlusive ovarian cancer
Hyperthermic intraperitoneal chemotherapy