IMR Press / EJGO / Volume 36 / Issue 5 / DOI: 10.12892/ejgo2735.2015

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research
DVP parametric imaging for characterizing ovarian masses in contrast-enhanced ultrasound
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1 Department of Gynaecology and Obstetrics, Renmin Hospital of Wuhan University, Wuhan, Hubei Province (China)
Eur. J. Gynaecol. Oncol. 2015, 36(5), 574–578;
Published: 10 October 2015

Aim: To evaluate whether parametric imaging with contrast-enhanced ultrasound is an approach capable of for the differential diagnosis of ovarian masses. Materials and Methods: The authors analysed 50 cases of ovarian masses by routine ultrasound and contrastenhanced ultrasound with a new dedicated parametric image processing software—Sonoliver. The angiogenesis and blood perfusion mode on a digital video recorder were recorded and the morphological characteristics of time-intensity curve (TIC) and dynamic vascular pattern (DVP) curve were subsequently described. The quantity factor, including time to peak (TTP), maximum intensity (IMAX), rise time, (RT), mean transit time (mTT), generated by Sonoliver software were compared in both histological gradings. Results: There were 24 cases (86%) displaying mainly hypo-enhanced with blue imaging in those with benign masses and 15 cases (68%) displaying mainly hyper-enhanced imaging with red in those with malignant masses. The difference was statistically significant (p < 0.05). DVP curves were unipolar below the baseline in 23 cases (82%) of benign masses and unipolar above the baseline in 15 cases (68%) of malignant masses. IMAX, TTP, and mTT were all significantly higher in those with malignant masses than those with benign ones (all p < 0.05), but, no statistical difference in the RT between the two groups was found (p > 0.05). Conclusions: According to the results, DVP parametric imaging is a new approach capable of differential diagnoses of overian masses with contrast-enhanced ultrasound.
Contrast-enhanced ultrasound
Time-intensity curve
Dynamic vascular pattern curve
Ovarian mass
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