IMR Press / EJGO / Volume 36 / Issue 4 / DOI: 10.12892/ejgo2669.2015

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Original Research
The opinion of gynecologists on the management of early-stage, high-grade endometrioid endometrial cancer
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1 Department of Obstetrics and Gynecology, Radboud university medical center, Nijmegen
2 ARTI Institute for Radiation Oncology, Arnhem
3 Department of Obstetrics and Gynecology, Canisius-Wilhelmina Hospital, Nijmegen
4 Department of Obstetrics and Gynecology, TweeSteden Hospital, Tilburg (The Netherlands)
Eur. J. Gynaecol. Oncol. 2015, 36(4), 402–405;
Published: 10 August 2015

Purpose of investigation: There is no consensus on the management of Stage I endometrioid endometrial cancer (EEC) with grade 3 histology. This study evaluates the opinion of gynecologists in The Netherlands on the management of Stage I, grade 3 EEC. Materials and Methods: Members of the Dutch Gynecologic Oncology Working Group were requested to complete a digital questionnaire on the management of Stage I, grade 3 EEC. Actual treatment of patients with Stage I, grade 3 EEC was assessed by analysis of PALGA, the Dutch Pathology Registry. Results: Most gynecologists prefer routine lymphadenectomy or complete staging (62.3%), while these were actually performed in 27.3% of the cases. Gynecologic oncologists are more likely to perform a lymphadenectomy than general gynecologists. There was a wide variation of clinical practice. Conclusion: The results of this study underline the need for additional research into management of Stage I, grade 3 EEC as well as the need for conclusive guidelines.
Endometrioid histology
Endometrial cancer
Grade 3
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