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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Multiorgan thrombotic disorder in a young patient with primary antiphospholipid syndrome (APS) and ovarian tumor
K. Jeremic1,3,*, A. Stefanovic1,3, A. Ljubic1,3, P. Miljic2,3, J. Stojnic1,3, B. Kastratovic1,3, L. J. Arsenijevic1
1 Clinic of Gynecology and Obstetrics, Clinical Centre of Serbia
2 Clinic of Haematology, Clinical Centre of Serbia
3 Medical School University of Belgrade (Serbia)
Eur. J. Gynaecol. Oncol. 2013, 34(3), 273–274;
Published: 10 June 2013
Catastrophic antiphospholipid syndrome (CAPS) is a life-threatening condition with high mortality rate besides aggressive multimodal treatment. Underlying triggers of “thrombotic and cytokine storm” include pregnancy, inflammation, trauma, surgery, and infection. The authors present a case of a young female patient with primary antiphospholipid syndrome (APS) who was admitted to the hospital due to abdominal pain caused by ovarian tumor with elevated tumor markers. After the prophylactic anticoagulants and antibiotic treatment, surgery was performed. Suddenly after treatment, her clinical status deteriorated and she died regardless of intensive immunosupresive and anticoagulant therapy attempts. This condition requires all clinical awareness, timely diagnosis, and therapeutical approach, including a better understanding of the pathophysiology that leads to CAPS.
Catastrophic antiphospholipid syndrome
Multiorgan thrombotic disorder
Systematic inflammatory response syndrome