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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Original Research
Multidisciplinary approach as the optimum for surgical treatment of retroperitoneal sarcomas in women
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Department of Obstetrics and Gynecology, Medical Faculty of the Charles University and Faculty Hospital, Hradec Kralove (Czech Republic)
Eur. J. Gynaecol. Oncol. 2013, 34(3), 234–237;
Published: 10 June 2013
Abstract
Introduction: The study aimed at evaluating surgical treatment results of retroperitoneal sarcomas (RPS) in female patients in terms of urological and oncological-gynecological collaboration. Materials and Methods: The authors performed a retrospective review of 17 women who underwent resection of a retroperitoneal tumor. The surgical results, complications, and both overall and disease-free survivals were evaluated. The assessment of a positive surgical margin and the size of the tumor were the second objective. The Kaplan-Meyer survival analysis was used for statistical evaluation. Results: The median follow-up was 60 (26 - 128) months. Themean age was 55.4 (35 - 75) years. The mean size of tumors was 14.8 (6 - 45) cm. Local recurrences were recorded in three patients, while distal metastases were reported in one patient. Two patients died of distal metastases. The overall and cancer-specific survival was 87.5% and disease-free survival was 76.5%. Conclusions: Complete resection is the only effective treatment of retroperitoneal sarcomas. Presence of positive surgical margin is connected with a high risk of local recurrence regardless of an adjuvant chemoand radiotherapy. The size of tumor had no impact on the survival or risk of local recurrence in the study group. The uro-gynecological collaboration was evaluated as well-suited in this part of oncological surgery.
Keywords
Retroperitoneal sarcoma
Leiomyosarcoma
Liposarcoma
Malignant fibrous histiocytoma
Multidisciplinary collaboration