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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
The correlation between expression of synuclein-γ, glucose transporter-1, and survival outcomes in endometrioid endometrial carcinoma
D. G. Hong1, N. Y. Park1, G. O. Chong1, Y. L. Cho1, I. S. Park1, M. J. Jeong2, J. Y. Park3, Y. S. Lee1,*
1 Gynecologic Cancer Center, Kyungpook National University Medical Center, Daegu
2 Department of Mathematics, Korea Science Academy of Korea Advanced Institute of Science and Technology, Pusan
3 Department of Pathology, Kyungpook National University Medical Center, Daegu (Republic of Korea)
Eur. J. Gynaecol. Oncol. 2013, 34(2), 128–131;
Published: 10 April 2013
Purpose: To evaluate the correlation between immunohistochemical expression of synuclein-γ, glucose transporter-1, and survival outcomes in endometrioid endometrial carcinoma. Materials and Methods: A tissue microarray was constructed using formalinfixed, paraffin-embedded tissue that included 23 early and 18 advanced cases. The intensity and area of the immunohistochemical reactions were evaluated using the semi-quantitative scoring system. Results: Synuclein-γ expression was higher in the advanced stage, although it was not statistically significant (p = 0.51). Glucose transporter-1 was overexpressed in the advanced stage (p = 0.01). Synuclein-γ (score = 0 vs > 0) and glucose transporter-1 (score ≤ 7 vs > 7) did not show any differences in overall survival (p = 0.54, p = 0.48) and disease-free survival (p = 0.61, p = 0.14). Conclusion: In this study the expression of synuclein-γ and glucose transporter-1 were not considered to be a prognostic factor and were not related with survival outcomes in endometrioid endometrial carcinoma.