IMR Press / EJGO / Volume 33 / Issue 5 / pii/1631087406078-1588983179

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
A case of occult bowel perforation after a cycle of chemotherapy for advanced epithelial ovarian carcinoma
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1 Department of Obstetrics and Gynecology, Renmin Hospital, Hubei University of Medicine, Shiyan, Hubei, China
Eur. J. Gynaecol. Oncol. 2012, 33(5), 540–542;
Published: 10 October 2012

Occult bowel perforation is a rare complication in chemotherapy of advanced epithelial ovarian cancer (EOC). The authors present a case of a 75-year-old woman who had appendectomy due to suppurative appendicitis five years prior, that experienced an occult bowel perforation resulting in continuous decline of electrolytes after a single cycle of nedaplatin (NDP) and paclitaxel during neoadjuvant treatment of advanced EOC. To the authors' knowledge, this is the first reported case of an occult bowel perforation after neoadjuvant chemotherapy (NAC) for ovarian cancer. The complication was highly suggestive of a cell lysis mechanism for the perforation.
Advanced epithelial ovarian cancer
Occult bowel perforation
Neoadjuvant chemotherapy
Cell lysis
CA 125
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