IMR Press / EJGO / Volume 32 / Issue 3 / pii/1630980233195-1982988982

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
Virilizing ovarian Krukenberg tumor in a 27-year-old pregnant woman. A case report and literature review
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1 Pathology Laboratory, Aretaieion University Hospital, Athens
2 2nd Department of Obstetrics and Gynecology, Aretaieion University Hospital, Athens (Greece)
Eur. J. Gynaecol. Oncol. 2011, 32(3), 331–333;
Published: 10 June 2011

A case is reported of a 27-year-old pregnant woman with ovarian tumors, measuring 12 cm and 11.5 cm in the greatest diameter, discovered during investigation for virilization symptoms. Termination of the pregnancy at the 22nd week of gestation and tumorectomy with both adnexa were performed, with the provisional diagnosis of arrhenoblastoma. Pathological examination of the tumors showed typical Krukenberg neoplasms and subsequent upper GI tract endoscopy revealed a gastric cancer that was excised. The pathological examination revealed a diffuse type gastric adenocarcinoma with signet ring morphology, similar to ovarian tumors. In any case of ovarian tumor with unusual hormonal manifestations, in addition to hormonally active sex cord-stromal neoplasms, metastatic ovarian tumors must be considered as well, especially in cases of bilateral tumors.
Ovarian metastatic tumor
Gastric cancer
Krukenberg tumor
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