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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Safety and efficacy of a splenectomy during debulking surgery for Müllerian carcinoma
T. Uehara1,*, T. Onda1, S. Togami1, T. Amano1, M. Tanikawa1, M. Sawada1, S. Ikeda1, T. Kato1, T. Kasamatsu1
1 Gynecologic Oncology Division, National Cancer Center Hospital, Tokyo (Japan)
Eur. J. Gynaecol. Oncol. 2011, 32(3), 269–273;
Published: 10 June 2011
Purpose: This study was designed to assess the safety and efficacy of a splenectomy and to analyze the prognostic factors of Mullerian carcinoma with spleen metastasis. Methods: We reviewed the medical records of 11 patients with Mullerian carcinoma who underwent a splenectomy between 1997 and 2007. The treatment outcome of these patients was examined and the possible prognostic factors were investigated by univariate analysis. Results: Four and seven patients underwent a splenectomy for primary and recurrent disease, respectively. A complete resection was achieved in eight patients. A blood transfusion was not required and only two mild postoperative complications were observed. The median and five-year survivals of all patients following treatment were 39 months and 39%, respectively. Older patients (_ 60 years old) and patients with a poor performance status (PS2) had a poorer prognosis by univariate analysis. Conclusions: A splenectomy can be performed safely and effectively during debulking surgery for appropriately selected patients with primary or recurrent Mullerian carcinoma.