Cite this article
Volume | Year
European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
The association of preoperative thrombocytosis with prognostic factors in malign ovarian tumor
U. Kuyumcuoglu1, A. I. Guzel1,*, Y. Celik2, M. Erdemog˘lu1
1 Department of Obstetrics and Gynecology, Faculty of Medicine, Diyarbakir
2 Department of Biostatistics and Medical Informatics Dicle University, Faculty of Medicine, Diyarbakir (Turkey)
Eur. J. Gynaecol. Oncol. 2010, 31(5), 514–516;
Published: 10 October 2010
Purpose: We assessed the association of preoperative thrombocytosis with prognostic factors in malign ovarian tumor. Methods: Over a five-year period, cases treated for ovarian cancer were randomly assigned. The data were collected from gynecological oncology, radiation oncology, medical oncology and pathology departments. Statistical analyses were carried out by using the statistical packages for SPSS 12.0 for Windows (Chicago, IL, USA). Survival was analyzed by the method of Kaplan and Meier, using log-rank (Mantel-Cox) analysis. Results: 51 cases with ovarian cancer were evaluated. Cases with thrombocytosis were found to have greater CA-125 levels, more advanced stage disease, more ascites and shorter periods of survival. Conclusion: Thrombocytosis is a poor prognostic factor in ovarian cancer. As reported previously, it is associated with aggressive tumor biology. Thus, preoperative thrombocytosis can be a used as a marker of poor outcomes.