IMR Press / EJGO / Volume 31 / Issue 4 / pii/1630985272341-856703365

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
A case of ovarian endometrioid adenocarcinoma with yolk sac tumor in a 35-year-old woman
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1 Department of Obstetrics and Gynecology, Kyungpook National University Hospital
2 Department of Pathology, Kyungpook National University Hospital, Daegu (Republic of Korea)
Eur. J. Gynaecol. Oncol. 2010, 31(4), 471–474;
Published: 10 August 2010

Ovarian yolk sac tumor (YST) is a malignant ovarian neoplasm differentiated from primordial germ cells that occur in young age, while endometrioid carcinoma (ECA) is a mullerian epithelial tumor that usually occurs in older patients. The coexistence of an ovarian ECA and YST component is very rare. Only 12 cases have been reported until now according to a Medline search of the English literatures. We present a case of a simultaneous ECA and a YST component in a 35-year-old woman. Exploratory laparotomy was performed. The parts of both ovaries that showed an endometrioid-like glandular pattern were positive for cytokeratin 7 and negative for AFP, but the YST component was negative for cytokeratin 7 and positive for AFP. After completion of four courses of BEP chemotherapy, two courses of taxane and carboplatin chemotherapy were added. The patient failed to respond and succumbed to the disease after 12 months of follow-up.
Endometrioid adenocarcinoma
Yolk sac tumor
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