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European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement with S.O.G.
Clinical features of 215 Stage I ovarian tumors in Japanese women
S. Kaku1,*, N. Takeshima1, K. Umayahara1, R. Furuta2, F. Akiyama2, K. Takizawa1
1 Department of Gynecology, 2Department of Pathology, Cancer Institute Hospital, Tokyo (Japan)
Eur. J. Gynaecol. Oncol. 2010, 31(4), 395–398;
Published: 10 August 2010
Purpose: Differences of the clinical features of Stage I borderline ovarian tumors and Stage I ovarian cancer need to be clarified. Methods: We retrospectively investigated 215 patients with Stage I ovarian tumors (67 with borderline tumors and 148 with ovarian cancer) treated between 1988 and 2001. Results: Only one patient with a borderline tumor developed recurrence, while recurrence was found in 20 patients with Stage I ovarian cancer. There was a significant difference in the recurrence rate between patients with Stage Ia or Ib ovarian cancer and those with Stage Ic cancer (p = 0.007). Clear cell adenocarcinoma showed a higher recurrence rate. Among our patients with recurrence, only five in whom the recurrent tumor could be surgically resected are currently alive and disease-free. Conclusions: This study confirmed the low aggressiveness of Stage I borderline ovarian tumors and high aggressiveness of Stage Ic ovarian cancer or clear cell adenocarcinoma. In patients with recurrence, surgical resection may improve survival.
Borderline ovarian tumors