IMR Press / EJGO / Volume 31 / Issue 3 / pii/1630985093106-1304040343

European Journal of Gynaecological Oncology (EJGO) is published by IMR Press from Volume 40 Issue 1 (2019). Previous articles were published by another publisher on a subscription basis, and they are hosted by IMR Press on as a courtesy and upon agreement with S.O.G.

Case Report
Ovarian metastasis of a primary renal cell carcinoma: case report and review of literature
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1 Department of Urology, Sisli Etfal Research and Training Hospital, Istanbul
1 Istanbul (Turkey)
2 Department of Medical Oncology, Istanbul
3 Department of Pathology, Istanbul
4 Department of Obstetrics and Gynecology, Okmeydani Research and Training Hospital
Eur. J. Gynaecol. Oncol. 2010, 31(3), 339–341;
Published: 10 June 2010

Ovarian metastases from renal cell carcinoma (RCC) are very rare, with only 23 cases reported in the literature. We report a case of 54-year-old women who developed bilateral ovarian metastasis 39 months after diagnosis of clear cell carcinoma. Total abdominal hysterectomy with bilateral salpingo-oophorectomy was carried out. Subsequently she was treated with sunitinib and her disease stabilized. She is still alive four years after diagnosis of the renal primary, and disease has stabilized on sunitinib. We conclude that, although rare, the possibility of metastatic RCC should be considered in the differential diagnosis of clear cell tumors of the ovary. Due to therapeutic and prognostic implications, it is very important to differentiate if the tumor is a primary ovarian tumor or a metastasis from a renal cell carcinoma. Early diagnosis of this rare metastatic tumor results in prompt treatment and prolonged patient survival.
Ovarian metastasis
Renal cell carcinoma
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